Patents by Inventor Leif Simonsson

Leif Simonsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5149523
    Abstract: Almokalant (p-INN), 4-[3-]ethyl[3-(propylsulfinyl)propyl]amino[-2-hydroxypropoxy]-benzonitrile , having the formula ##STR1## is a member of a group of compounds useful in the treatment of cardiac arrhythmias. Enhanced stability, palatability, and technical properties of almokalant can be achieved when it is complexed as a salt with polystyrenesulfonic acid. Accordingly, the invention encompasses the almokalant salt and processes for the preparation of said salt. The invention further encompasses solid oral pharmaceutical dosage forms containing the almokalant-polystyrenesulfonate complex as well as methods for their manufacture as medicaments with action against cadiac arrhythmias.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: September 22, 1992
    Assignee: Aktiebolaget Hassle
    Inventors: Per J. Lundberg, Karin Wingstrand, Kjell H. Andersson, Leif Simonsson