Abstract: The invention relates to a breath test system that is unobtrusive in that it does not require a person subjected to the system to take any other action to breath. It comprises a sensor unit (5) configured to sense the presence or concentration of a volatile substance, present in air flowing through a predefined inlet area (4), and to generate a signal corresponding to the concentration of said substance. There is also provided an apparatus (2, 3) configured to detect the presence of a person at a position in the vicinity of said input area, and having means for registering said presence, and further configured to respond to said presence by delivering an output. This said apparatus includes a unit configured to call for immediate attention of said person, upon said registration of the presence of said person, and a unit configured to provide instructions to said person to direct an expiratory air flow towards said inlet area (4).

Abstract: The invention relates to a system for breath test of a person. It includes a sensor unit configured to sense the presence/concentration of a volatile substance, e.g. alcohol, present in air flowing through a predefined inlet area and generating a signal corresponding to the concentration of said substance. An analyzer determines the concentration of said substance in the breath of said person. It comprises means for the temporary interruption of said air flow at a point in time coinciding with the detection of a breath. It also relates to a method comprising interrupting the flow through said predefined area for a predetermined period of time, and detecting the concentration of said substance during said interruption.

Abstract: A breath test system is provided comprising a sensor unit configured to sense the presence or concentration of a volatile substance present in air flowing through a predefined inlet area, and generate a signal corresponding to the concentration of said substance. Also provided is an apparatus configured to detect the presence of a person in the vicinity of said input area, and registering said presence, and configured to respond by delivering an output. This apparatus includes a unit configured to call for immediate attention of said person, and upon registration of the presence of said person, provide instructions to said person to direct an expiratory air flow towards said inlet area. An analyzer to determine breath substance concentration of said person is also provided, the determination based on said signal corresponding to the substance concentration.

Abstract: Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

Abstract: The invention relates to a system for breath test of a person. It includes a sensor unit configured to sense the presence/concentration of a volatile substance, e.g. alcohol, present in air flowing through a predefined inlet area and generating a signal corresponding to the concentration of said substance. An analyzer determines the concentration of said substance in the breath of said person. It comprises means for the temporary interruption of said air flow at a point in time coinciding with the detection of a breath. It also relates to a method comprising interrupting the flow through said predefined area for a predetermined period of time, and detecting the concentration of said substance during said interruption.

Abstract: The invention relates to a system for breath test of a person. It includes a sensor unit configured to sense the presence/concentration of a volatile substance, e.g. alcohol, present in air flowing through a predefined inlet area and generating a signal corresponding to the concentration of said substance. An analyzer determines the concentration of said substance in the breath of said person. It comprises means for the temporary interruption of said air flow at a point in time coinciding with the detection of a breath. It also relates to a method comprising interrupting the flow through said predefined area for a predetermined period of time, and detecting the concentration of said substance during said interruption.

Abstract: Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

Abstract: The invention relates to a system for breath test of a person. It includes a sensor unit configured to sense the presence/concentration of a volatile substance, e.g. alcohol, present in air flowing through a predefined inlet area and generating a signal corresponding to the concentration of said substance. An analyzer determines the concentration of said substance in the breath of said person. It comprises means for the temporary interruption of said air flow at a point in time coinciding with the detection of a breath. It also relates to a method comprising interrupting the flow through said predefined area for a predetermined period of time, and detecting the concentration of said substance during said interruption.

Abstract: The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics wherein the amino acid at position (1) is changed to Ile or Gly, the amino acid at position (4) is changed to an Ala, the amino acid at position (4) is removed, the amino acid at position (5) is changed to an Ala, or wherein, as in the case of MU1140, the amino acid at position (13) is Arg, the Arg at position (13) is substituted with Asp, or combinations of two or more these changes or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a sensor and guide wire assembly (21) for intravascular measurements of physiological variables in a living body, comprising a core wire (22), a first coil (23), a jacket (24), and a second coil (25). The jacket (24) comprises a first end portion (24a), which is crimped onto the core wire (22) and over which a portion of the first coil (23) is threaded, and a second end portion (24b), which is crimped onto the core wire (22) and over which a portion of the second coil (25) is threaded.

Abstract: Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

Abstract: A multifunctional breath analyzer includes a receptor unit for receiving a breath sample from a test subject, a sensing unit providing a signal corresponding to the concentration of at least one volatile substance within the sample, elements for providing a signal indicative of the dilution of the breath sample, and an analyzing unit/processing unit for the identification and quantification of the volatile substance of the breath sample. The signal processing unit is configured to perform at least two different calculations for the quantification, and the signal processing unit is also configured to automatically display the result of a selected calculation, the selection being based on the signal indicating dilution.

Abstract: Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

Abstract: The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.

Abstract: The present invention provides methods for adding functional hydrophobic, charge, polar, and other structural groups on antimicrobial compounds for enhancing the physicochemical properties of the antimicrobial compounds, thereby creating novel antimicrobial analogs with enhanced functions.

Abstract: The invention relates to a system for breath test of a person. It includes a sensor unit configured to sense the presence/concentration of a volatile substance, e.g. alcohol, present in air flowing through a predefined inlet area and generating a signal corresponding to the concentration of said substance. An analyzer determines the concentration of said substance in the breath of said person. It comprises means for the temporary interruption of said air flow at a point in time coinciding with the detection of a breath. It also relates to a method comprising interrupting the flow through said predefined area for a predetermined period of time, and detecting the concentration of said substance during said interruption.

Abstract: A breath test system is provided comprising a sensor unit configured to sense the presence or concentration of a volatile substance present in air flowing through a predefined inlet area, and generate a signal corresponding to the concentration of said substance. Also provided is an apparatus configured to detect the presence of a person in the vicinity of said input area, and registering said presence, and configured to respond by delivering an output. This apparatus includes a unit configured to call for immediate attention of said person, and upon registration of the presence of said person, provide instructions to said person to direct an expiratory air flow towards said inlet area. An analyzer to determine breath substance concentration of said person is also provided, the determination based on said signal corresponding to the substance concentration.

Abstract: The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics wherein the amino acid at position (1) is changed to Ile or Gly, the amino acid at position (4) is changed to an Ala, the amino acid at position (4) is removed, the amino acid at position (5) is changed to an Ala, or wherein, as in the case of MU1140, the amino acid at position (13) is Arg, the Arg at position (13) is substituted with Asp, or combinations of two or more these changes or a pharmaceutically acceptable salt thereof.

Abstract: A transmitter unit with an attachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The attachable energy source can be a battery pack or battery holder provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.

Abstract: The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.