Patents by Inventor Leif Strandberg

Leif Strandberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE-BASED PASSIVE IMMUNIZATION THERAPY FOR THE TREATMENT OF ATHEROSCLEROSIS
    Publication number: 20120070426
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Application
    Filed: October 13, 2011
    Publication date: March 22, 2012
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Peptide-based passive immunization therapy for treatment of atherosclerosis
    Patent number: 8114966
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: February 14, 2012
    Assignee: Forskarpatent I SYD AB
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Peptide-based passive immunization therapy for treatment of atherosclerosis
    Patent number: 7601353
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: October 13, 2009
    Assignee: Forskarpatent I SYD AB
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Methods and compositions for impairing multiplication of HIV-1
    Patent number: 7563437
    Abstract: A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: July 21, 2009
    Assignee: Thymon, LLC
    Inventors: Roland Carlsson, Elisabeth Sonesson, Yvonne Stenberg, Leif Strandberg, Gideon Goldstein
  • PEPTIDE-BASED PASSIVE IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS
    Publication number: 20090155258
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Application
    Filed: October 27, 2008
    Publication date: June 18, 2009
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Antibody immunization therapy for treatment of atherosclerosis
    Patent number: 7521046
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: April 21, 2009
    Assignee: BIOINVENT International AB
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Antibody immunization therapy for treatment of atherosclerosis
    Patent number: 7468183
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: December 23, 2008
    Assignee: Forskarpatent I Syd AB
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • ANTIBODY IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS
    Publication number: 20080075716
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Application
    Filed: October 30, 2007
    Publication date: March 27, 2008
    Applicant: BIOINVENT INTERNATIONAL AB
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Peptide-based passive immunization therapy for treatment of atherosclerosis
    Publication number: 20070098723
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Application
    Filed: December 30, 2005
    Publication date: May 3, 2007
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Methods and compositions for impairing multiplication of HIV-1
    Publication number: 20060211108
    Abstract: A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.
    Type: Application
    Filed: February 13, 2006
    Publication date: September 21, 2006
    Applicant: Thymon, L.L.C.
    Inventors: Roland Carlsson, Elisabeth Sonesson, Yvonne Stenberg, Leif Strandberg, Gideon Goldstein
  • Novel composition
    Publication number: 20050287137
    Abstract: The present invention relates to novel therapies and treatments of atherosclerotic diseases. Accordingly there is provided, methods of treating or preventing atherosclerosis by passive vaccination through administration to a patient of a fully human antibody that is capable of binding to the specific fragments of ApoCIII. Specific human monoclonal antibodies and their use in therapy of atherosclerosis is provided. There is further provided the use of the antibodies of the present invention in medicine.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 29, 2005
    Inventors: Patrick Dhaese, Pascal Mettens, Rene Meykens, Philippe Monteyne, Torbjorn Schiott, Leif Strandberg
  • Peptide-based passive immunization therapy for treatment of atherosclerosis
    Publication number: 20040202653
    Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
    Type: Application
    Filed: October 3, 2003
    Publication date: October 14, 2004
    Inventors: Jan Nilsson, Roland Carlsson, Jenny Bengtsson, Leif Strandberg
  • Novel composition
    Publication number: 20040185044
    Abstract: The present invention relates to novel therapies and treatments of atherosclerotic diseases. Accordingly there is provided, methods of treating or preventing atherosclerosis by passive vaccination through administration to a patient of a fully human antibody that is capable of binding to the specific fragments of ApoCIII. Specific human monoclonal antibodies and their use in therapy of atherosclerosis is provided. There is further provided the use of the antibodies of the present invention in medicine.
    Type: Application
    Filed: July 15, 2003
    Publication date: September 23, 2004
    Inventors: Patrick Dhaese, Pascal Mettens, Rene Meykens, Philippe Monteyne, Torbjorn Schiott, Leif Strandberg