Abstract: This invention provides a class of 3-amino-7H-thieno[2,3-b]pyridin-6-one derivatives, substituted in the 7-position by an aryl, heteroaryl, cycloalkyl or heterocycloalkyl moiety, and in the 2-position by a specified range of substituent groups; also provided is a process for preparing those compounds, and the use thereof as intermediates in the manufacture of certain p38 MAP kinase inhibitors.

Abstract: A multi-stream fuel injector for a gas turbine engine comprises a plurality of concentric member which define a plurality of flow passages carrying HP compressor air or fuel/air mixture. One of the members is formed with a wide-angle, frusto-conical flared lip to propagate a wide-angle fuel/air mixture cone in the combustion region. The lip is of such a cross-sectional configuration that air flowing over the lip surface remains attached to the surface and flows in a non-turbulent manner, initially in a radially inward direction, and subsequently in a radially outward direction. The lip ensures that undesirable regions of recirculation are avoided around the fuel injector.

Abstract: An annular combustor structure particularly suited to staged combustion has a faired centrebody incorporating a diffuser in the head of the combustor. The structure carries fuel injector mountings for pilot and main stage combustion which receive fuel from respective manifolds running around the hollow interior of the structure. There are two annular chambers each containing a fuel manifold, and cooling air passes through the chambers before entering the combustion volume. The manifolds are connected to an external source of fuel by conduits which pass radially through the combustion chamber outer casing walls.

Abstract: Gas turbine engine combustor designs are tending to higher operating temperatures and, therefore, utilisation of high temperature materials such as, for example, ceramics, composite material and high temperature nickel alloys. However use of these materials for combustor components leads, in turn, to problems of how to join together those components. A high temperature material combustor barrel and a similar combustor head heatshield are joined to a metal or metal alloy combustor head by means of a lip around the circumference of the head swaged or rolled onto a lip on the barrel trapping the heatshield between them.