Patents by Inventor Leila Malik

Leila Malik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW METHODS FOR MAKING BARUSIBAN AND ITS INTERMEDIATES
    Publication number: 20180282367
    Abstract: The present invention relates to new solid phase peptide methods for synthesizing analogues that exhibit oxytocin antagonist activity, specifically Barusiban and its intermediates. Specifically, the present invention relates to a solid phase process for preparing a compound having the formula c[AA1-AA6]-AA7-ol, wherein AA1 is propionic acid, AA2 is preferably D-Trp, AA3 is Ile, AA4 is preferably AlloIle, AA5 is Asn, AA6 is hCy, and AA7 is preferably N-Me-Orn-ol, or a pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 4, 2018
    Inventors: Leila Malik, Kazimierz Wisniewski, Chantal Devin
  • Antisense Modulation of CD40 Expression
    Publication number: 20070161589
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CD40. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40. Methods of using these compounds for modulation of CD40 expression and for treatment of diseases associated with CD40 are provided.
    Type: Application
    Filed: August 22, 2006
    Publication date: July 12, 2007
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: C. Bennett, Lex Cowsert, Leila Malik, Andrew Siwkowski, Anne Eldrup
  • Compounds useful for the treatment and prevention of pain and screening methods therefor
    Publication number: 20060217370
    Abstract: The present invention relates to the composition of compounds having the generic structure: and to a method of treatment or prevention of pain using the above compounds.
    Type: Application
    Filed: February 21, 2006
    Publication date: September 28, 2006
    Inventors: Ethan Burstein, Leila Malik, Nicholas Kelly
  • Antisense modulation of CD40 expression
    Publication number: 20040186071
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CD40. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40. Methods of using these compounds for modulation of CD40 expression and for treatment of diseases associated with CD40 are provided.
    Type: Application
    Filed: October 31, 2003
    Publication date: September 23, 2004
    Inventors: C. Frank Bennett, Lex M. Cowsert, Leila Malik, Andrew Siwkowski, Anne B. Eldrup
  • Modified peptide nucleic acid (PNA) molecules
    Publication number: 20030199431
    Abstract: The present invention relates to novel drugs which may be used in combating infectious micro-organisms, particularly bacteria.
    Type: Application
    Filed: March 27, 2002
    Publication date: October 23, 2003
    Inventors: Peter E. Nielsen, Liam Good, Henrik Frydenlund Hansen, Frederik Beck, Leila Malik, Carsten Schou, Margit Wissenbach, Birgit Kjaeldgaard Giwercman
  • Modified peptide nucleic acid (PNA) molecules
    Publication number: 20030176325
    Abstract: The present invention relates to novel drugs which may be used in combating infectious micro-organisms, particularly bacteria.
    Type: Application
    Filed: October 19, 2001
    Publication date: September 18, 2003
    Applicant: Pantheco A/S and Peter E. Nielsen
    Inventors: Peter E. Nielsen, Liam Good, Henrik Frydenlund Hansen, Frederik Beck, Leila Malik, Carsten Schou, Margit Wissenbach, Birgit Kjaeldgaard Giwercman
  • Modified peptide nucleic acid (PNA) molecules
    Patent number: 6548651
    Abstract: The present invention relates to novel drugs which may be used in combating infectious micro-organisms, particularly bacteria. More specifically, the invention relates to peptide nucleic acid (PNA) sequences that are modified by conjugating cationic peptides to the PNA moiety in order to obtain novel PNA molecules that exhibit enhanced anti-infective properties.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: April 15, 2003
    Assignees: Pantheco A/S
    Inventors: Peter E. Nielsen, Liam Good, Henrik Frydenlund Hansen, Frederik Beck, Leila Malik, Carsten Schou, Margit Wissenbach, Birgit Kjaeldgaard Giwercman