Patents by Inventor Leila Shepherd

Leila Shepherd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200131572
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Application
    Filed: January 2, 2020
    Publication date: April 30, 2020
    Applicant: DNAE Group Holdings Limited
    Inventors: Zahid ANSARI, Krishna AMIN, Ginny JORGENSEN, Kurt KOLB, Daniel MORLEY, Alpesh PATEL, Samuel REED, Leila SHEPHERD, Christofer TOUMAZOU
  • Patent number: 10557168
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: February 11, 2020
    Assignee: DNAE Group Holdings Limited
    Inventors: Zahid Ansari, Krishna Amin, Ginny Jorgensen, Kurt Kolb, Daniel Morley, Alpesh Patel, Samuel Reed, Leila Shepherd, Christofer Toumazou
  • Publication number: 20190249246
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 15, 2019
    Applicant: DNAE Group Holdings Limited
    Inventors: Zahid ANSARI, Krishna AMIN, Ginny JORGENSEN, Kurt KOLB, Daniel MORLEY, Alpesh PATEL, Samuel REED, Leila SHEPHERD, Christofer TOUMAZOU
  • Patent number: 10316363
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: June 11, 2019
    Assignee: DNAE Group Holdings Limited
    Inventors: Zahid Ansari, Krishna Amin, Ginny Jorgensen, Kurt Kolb, Daniel Morley, Alpesh Patel, Samuel Reed, Leila Shepherd, Christofer Toumazou
  • Publication number: 20170226579
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Applicant: DNAE Group Holdings Limited
    Inventors: Zahid ANSARI, Krishna AMIN, Ginny JORGENSEN, Kurt KOLB, Daniel MORLEY, Alpesh PATEL, Samuel REED, Leila SHEPHERD, Christofer TOUMAZOU
  • Publication number: 20150240300
    Abstract: Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.
    Type: Application
    Filed: July 18, 2013
    Publication date: August 27, 2015
    Inventors: Zahid Ansari, Alpesh Patel, Krishna Amin, Ginny Jorgensen, Kurt Kolb, Daniel Morley, Sam Reed, Leila Shepherd, Christofer Toumazou
  • Publication number: 20100159461
    Abstract: According to a first aspect of the present invention there is provided a digital signal processing circuit, one or more switches of the circuit being provided by an ion sensitive field effect transistor.
    Type: Application
    Filed: December 2, 2009
    Publication date: June 24, 2010
    Applicant: DNA Electronics Ltd.
    Inventors: Christofer Toumazou, Bhusana Premanode, Leila Shepherd
  • Patent number: 7649358
    Abstract: A signal processing circuit includes an ion sensitive field effect transistor, a reference electrode for the ion sensitive field effect transistor, a metal oxide semiconductor transistor having its gate coupled to the reference electrode, and a biasing circuit. The biasing circuit is configured to bias the ion sensitive field effect transistor and the metal oxide semiconductor field effect transistor to operate in a weak inversion region and to provide an output current signal.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: January 19, 2010
    Assignee: DNA Electronics Ltd.
    Inventors: Christofer Toumazou, Bhusana Premanode, Leila Shepherd
  • Publication number: 20080265985
    Abstract: A signal processing circuit comprising one or more ion sensitive field effect transistors, ISFETs, and a biasing circuit for biasing the or each ion sensitive field effect transistor to operate in the weak inversion region.
    Type: Application
    Filed: June 22, 2005
    Publication date: October 30, 2008
    Applicant: DNA ELECTRONICS LTD.
    Inventors: Christofer Toumazou, Bhusana Premanode, Leila Shepherd