Patents by Inventor Leilei YU

Leilei YU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12280079
    Abstract: The disclosure discloses a strain of Lactobacillus crispatus capable of preventing and/or treating Helicobacter pylori infection, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain of Lactobacillus crispatus CCFM1118. The Lactobacillus crispatus CCFM1118 can inhibit Helicobacter pylori, specifically embodied in that: (1) the diameter of an inhibition zone of supernatant of the Lactobacillus crispatus CCFM1118 on Helicobacter pylori can reach 13.14 mm; and (2) the Lactobacillus crispatus CCFM1118 can significantly reduce the adhesion of Helicobacter pylori to AGS cells. Therefore, the Lactobacillus crispatus CCFM1118 has great application prospects in inhibiting Helicobacter pylori (not for the purposes of disease diagnosis and treatment) and preparing Helicobacter pylori inhibitors.
    Type: Grant
    Filed: March 31, 2022
    Date of Patent: April 22, 2025
    Assignee: Jiangnan University
    Inventors: Qixiao Zhai, Wei Chen, Meiyi Zhang, Leilei Yu, Fengwei Tian, Shunhe Wang, Jianxin Zhao, Hao Zhang
  • Patent number: 12275934
    Abstract: The disclosure discloses a strain of Lactobacillus rhamnosus and application thereof in inhibiting Helicobacter pylori, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain of Lactobacillus rhamnosus CCFM1119. The Lactobacillus rhamnosus CCFM1119 can prevent and/or treat Helicobacter pylori infection, specifically embodied in that: (1) the Lactobacillus rhamnosus CCFM1119 can significantly relieve the gastrointestinal symptoms of patients with Helicobacter pylori infection; (2) the Lactobacillus rhamnosus CCFM1119 can significantly reduce the amount of colonization of Helicobacter pylori in patients with Helicobacter pylori infection; and (3) the Lactobacillus rhamnosus CCFM1119 can significantly increase the clearance rate of Helicobacter pylori in patients with Helicobacter pylori infection.
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: April 15, 2025
    Assignee: Jiangnan University
    Inventors: Qixiao Zhai, Wei Chen, Jianxin Zhao, Meiyi Zhang, Shumao Cui, Wenwei Lu, Fengwei Tian, Leilei Yu, Gang Wang, Hao Zhang
  • Patent number: 12098047
    Abstract: For the defects that manual adhesive tape pasting is low in efficiency and high in cost, and it is difficult to automatically paste adhesive tapes at specified positions of inner and outer surfaces of an item according to a certain length through a handheld box sealer and an adhesive tape seal pasting mechanism, a cantilever type plane automatic adhesive tape pasting device is invented. A liftable two-stage telescopic cantilever adhesive tape pasting head structure, a roller type automatic adhesive tape feeding structure, an adjustable fixed-length cutting structure and a roller type pasting structure are adopted for the device to achieve the automatic adhesive tape pasting on inner and outer side planes of an item. After the item needing adhesive tape pasting is positioned, the pasting process is completely automatically conducted without manual participation, the labor intensity is reduced, the labor efficiency is improved.
    Type: Grant
    Filed: November 11, 2021
    Date of Patent: September 24, 2024
    Assignee: Qingdao University of Science and Technology
    Inventors: Shibao Wen, Yi Li, Chenxi Nie, Qin Du, Yuwei Feng, Luyao Wang, Shuo Wang, Leilei Yu
  • Publication number: 20230278824
    Abstract: For the defects that manual adhesive tape pasting is low in efficiency and high in cost, and it is difficult to automatically paste adhesive tapes at specified positions of inner and outer surfaces of an item according to a certain length through a handheld box sealer and an adhesive tape seal pasting mechanism, a cantilever type plane automatic adhesive tape pasting device is invented. A liftable two-stage telescopic cantilever adhesive tape pasting head structure, a roller type automatic adhesive tape feeding structure, an adjustable fixed-length cutting structure and a roller type pasting structure are adopted for the device to achieve the automatic adhesive tape pasting on inner and outer side planes of an item. After the item needing adhesive tape pasting is positioned, the pasting process is completely automatically conducted without manual participation, the labor intensity is reduced, the labor efficiency is improved.
    Type: Application
    Filed: November 11, 2021
    Publication date: September 7, 2023
    Inventors: Shibao Wen, Yi Li, Chenxi Nie, Qin Du, Yuwei Feng, Luyao Wang, Shuo Wang, Leilei Yu
  • Publication number: 20220228106
    Abstract: The disclosure discloses a strain of Lactobacillus rhamnosus and application thereof in inhibiting Helicobacter pylori, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain of Lactobacillus rhamnosus CCFM1119. The Lactobacillus rhamnosus CCFM1119 can prevent and/or treat Helicobacter pylori infection, specifically embodied in that: (1) the Lactobacillus rhamnosus CCFM1119 can significantly relieve the gastrointestinal symptoms of patients with Helicobacter pylori infection; (2) the Lactobacillus rhamnosus CCFM1119 can significantly reduce the amount of colonization of Helicobacter pylori in patients with Helicobacter pylori infection; and (3) the Lactobacillus rhamnosus CCFM1119 can significantly increase the clearance rate of Helicobacter pylori in patients with Helicobacter pylori infection.
    Type: Application
    Filed: April 1, 2022
    Publication date: July 21, 2022
    Inventors: Qixiao ZHAI, Wei CHEN, Jianxin ZHAO, Meiyi ZHANG, Shumao CUI, Wenwei LU, Fengwei TIAN, Leilei YU, Gang WANG, Hao ZHANG
  • Publication number: 20220218769
    Abstract: The disclosure discloses a strain of Lactobacillus crispatus capable of preventing and/or treating Helicobacter pylori infection, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain of Lactobacillus crispatus CCFM1118. The Lactobacillus crispatus CCFM1118 can inhibit Helicobacter pylori, specifically embodied in that: (1) the diameter of an inhibition zone of supernatant of the Lactobacillus crispatus CCFM1118 on Helicobacter pylori can reach 13.14 mm; and (2) the Lactobacillus crispatus CCFM1118 can significantly reduce the adhesion of Helicobacter pylori to AGS cells. Therefore, the Lactobacillus crispatus CCFM1118 has great application prospects in inhibiting Helicobacter pylori (not for the purposes of disease diagnosis and treatment) and preparing Helicobacter pylori inhibitors.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Inventors: Qixiao ZHAI, Wei CHEN, Meiyi ZHANG, Leilei YU, Fengwei TIAN, Shunhe WANG, Jianxin ZHAO, Hao ZHANG