Patents by Inventor Leitao ZHANG

Leitao ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240107855
    Abstract: A display panel is provided. The display panel includes: a pixel definition layer including light-emitting openings in an array distribution; a light-emitting layer disposed in the light-emitting openings; and photosensitive elements disposed above the pixel definition layer, wherein projections of the photosensitive elements on the pixel definition layer are located outside the light-emitting openings. According to the present disclosure, the photosensitive elements are disposed obliquely above the light-emitting openings of the display panel. In this way, the photosensitive elements can more effectively sense the light emitted upward from the light-emitting layer and perform signal feedback.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 28, 2024
    Inventors: Leitao Sun, Wenxu Xianyu, Chunpeng Zhang, Zhimeng Luo
  • Publication number: 20230203060
    Abstract: Provided are a fused tricyclic compound having the structure shown in formula (I), a pharmaceutical composition thereof, and a use thereof. The fused tricyclic compound serves as a selective inhibitor of KRAS mutation, and has high activity, good selectivity. and reduced toxic side effects.
    Type: Application
    Filed: May 27, 2021
    Publication date: June 29, 2023
    Inventors: Fusheng ZHOU, Tao JIANG, Yingtao LIU, Jichen ZHAO, Wan HE, Zhubo LIU, Ling PENG, Lijian CAI, Leitao ZHANG, Chonglan LIN, Huabin YANG, Tao ZHANG, Jiong LAN
  • Publication number: 20230139111
    Abstract: Provided are a dihydronaphthyridinone compound as shown in formula (I), which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof. In addition, provided are a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.
    Type: Application
    Filed: February 9, 2021
    Publication date: May 4, 2023
    Applicants: GENFLEET THERAPEUTICS (SHANGHAI) INC., ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
    Inventors: Fusheng ZHOU, Xiaoming XU, Leitao ZHANG, Xin LI, Lili TANG, Jiong LAN
  • Publication number: 20220363681
    Abstract: Provided is an oxygen-substituted six-membered ring pyrimidine compound with selective inhibitory effect on KRAS gene mutation and a pharmaceutically acceptable salt, a stereoisomer, a solvate, or a prodrug thereof, as represented by formula (I). The definition of each group or symbol in the formula is detailed in the specification. Moreover, a pharmaceutical composition containing the compound and an application thereof in the preparation of cancer drugs are also provided.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 17, 2022
    Inventors: Fusheng ZHOU, Tao JIANG, Wan HE, Zhubo LIU, Leitao ZHANG, Jiong LAN
  • Publication number: 20220251109
    Abstract: An oxaazaquinazolin-7(8H)-ketone compound with a selective inhibition effect on KRAS gene mutation and pharmaceutically acceptable salts thereof, stereoisomers, solvent compounds or prodrugs (as shown in formula I or formula II, see the details of the definition to each group in the formulas in the specification), as well as the pharmaceutical composition containing the compound, and the application thereof in preparation of cancer medicine.
    Type: Application
    Filed: April 28, 2020
    Publication date: August 11, 2022
    Applicants: GENFLEET THERAPEUTICS (SHANGHAI) INC., ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
    Inventors: Fusheng ZHOU, Lijian CAI, Tao JIANG, Jichen ZHAO, Yingtao LIU, Jinzhu ZHAO, Leitao ZHANG, Zhubo LIU, Ling PENG, Wan HE, Huabin YANG, Tao ZHANG, Qian DING, Biao ZHENG, Qiang LV, Jiong LAN
  • Publication number: 20220235032
    Abstract: A substituted dihydropyrazole compound as shown in formula I, which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, wherein the definition of each group in the formula is detailed in the description. In addition is a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.
    Type: Application
    Filed: May 9, 2020
    Publication date: July 28, 2022
    Applicants: GENFLEET THERAPEUTICS (SHANGHAI) INC., ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
    Inventors: Fusheng ZHOU, Xiaoming XU, Leitao ZHANG, Tao JIANG, Yingtao LIU, Jiong LAN
  • Publication number: 20220177462
    Abstract: A substituted heterocyclic amide compound having a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use of same in the preparation of a drug for treating a RIPK1-related diseases or conditions.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 9, 2022
    Applicants: GENFLEET THERAPEUTICS (SHANGHAI) INC., ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
    Inventors: Fusheng ZHOU, Xiaoming XU, Leitao ZHANG, Zhubo LIU, Gang HU, Qian DING, Fubo XIE, Biao ZHENG, Qiang LV, Jiong LAN
  • Patent number: 10793549
    Abstract: The present invention relates to a sulfuryl-substituted benzoheterocyclic derivative, a preparation method and medical use thereof. Particularly, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, and a preparation method and application thereof. The definition of each group in the formula can be found in the specification and the claims.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: October 6, 2020
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yunzhou Jin, Xiang Chen, Pengfei Cheng, Ping Bu, Leitao Zhang, Chong Wen, Yingtao Liu, Fusheng Zhou, Ming Weng, Jiong Lan
  • Patent number: 10604417
    Abstract: The present application provides a method for preparing lanthanide fluoride two-dimensional porous nanosheets and belongs to the field of novel materials. In the present application, mixing a water-soluble lanthanide metal salt and an aqueous solution of sodium acetate in a nitrogen atmosphere to obtain a mixed solution, and adding an aqueous solution of fluorine-containing salt to the mixed solution obtained for precipitation reaction to produce lanthanide fluoride two-dimensional porous nanosheets. In the preparation process provided by the present application, no additional surfactant or template agent needs to be added, the pollution of the surfactant to the surface of the prepared material is avoided and the tedious after-treatment steps to template agent are reduced. Accordingly, the large-scale production can be realized, and the lanthanide fluoride two-dimensional porous nanosheets constructed by nanoparticles are prepared in large scale by one step.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: March 31, 2020
    Assignee: TIANJIN POLYTECHNIC UNIVERSITY
    Inventors: Yuzhong Zhang, Leitao Zhang, Hong Li
  • Publication number: 20190322541
    Abstract: The present application provides a method for preparing lanthanide fluoride two-dimensional porous nanosheets and belongs to the field of novel materials. In the present application, mixing a water-soluble lanthanide metal salt and an aqueous solution of sodium acetate in a nitrogen atmosphere to obtain a mixed solution, and adding an aqueous solution of fluorine-containing salt to the mixed solution obtained for precipitation reaction to produce lanthanide fluoride two-dimensional porous nanosheets. In the preparation process provided by the present application, no additional surfactant or template agent needs to be added, the pollution of the surfactant to the surface of the prepared material is avoided and the tedious after-treatment steps to template agent are reduced. Accordingly, the large-scale production can be realized, and the lanthanide fluoride two-dimensional porous nanosheets constructed by nanoparticles are prepared in large scale by one step.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 24, 2019
    Inventors: YUZHONG ZHANG, LEITAO ZHANG, HONG LI
  • Publication number: 20190300506
    Abstract: The present invention relates to a sulfonyl-substituted benzoheterocyclic derivative, a preparation method and medical use thereof. Particularly, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, and a preparation method and application thereof. The definition of each group in the formula can be found in the specification and the claims.
    Type: Application
    Filed: November 10, 2017
    Publication date: October 3, 2019
    Inventors: Yunzhou JIN, Xiang CHEN, Pengfei CHENG, Ping BU, Leitao ZHANG, Chong WEN, Yingtao LIU, Fusheng ZHOU, Ming WENG, Jiong LAN