Patents by Inventor Lelia Wolf-van Buerck

Lelia Wolf-van Buerck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pancreatic islets of transgenic LEA29Y animals for treating diabetes
    Patent number: 10286013
    Abstract: The present invention relates to methods of treating diabetes in a human subject comprising the use of pancreatic islets or of embryonic pancreatic tissue of a transgenic animal, wherein said transgenic animal contains a polynucleotide sequence encoding a CTLA4 peptide-immunoglobulin fusion, preferably LEA29Y, and expresses said CTLA4 peptide-immunoglobulin fusion in a tissue-specific manner in pancreatic islets.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: May 14, 2019
    Assignee: MWM BIOMODELS GMBH
    Inventors: Eckhard Wolf, Nikolai Klymiuk, Lelia Wolf-Van Buerck, Jochen Seißler
  • Pancreatic Islets of Transgenic LEA29Y Animals for Treating Diabetes
    Publication number: 20170042942
    Abstract: The present invention relates to methods of treating diabetes in a human subject comprising the use of pancreatic islets or of embryonic pancreatic tissue of a transgenic animal, wherein said transgenic animal contains a polynucleotide sequence encoding a CTLA4 peptide-immunoglobulin fusion, preferably LEA29Y, and expresses said CTLA4 peptide-immunoglobulin fusion in a tissue-specific manner in pancreatic islets.
    Type: Application
    Filed: October 27, 2016
    Publication date: February 16, 2017
    Inventors: Eckhard WOLF, Nikolai KLYMIUK, Lelia WOLF-VAN BUERCK, Jochen SEIßLER
  • Pancreatic islets of transgenic LEA29Y animals for treating diabetes
    Publication number: 20140112958
    Abstract: The present invention relates to methods of treating diabetes in a human subject comprising the use of pancreatic islets or of embryonic pancreatic tissue of a transgenic animal, wherein said transgenic animal contains a polynucleotide sequence encoding a CTLA4 peptide-immunoglobulin fusion, preferably LEA29Y, and expresses said CTLA4 peptide-immunoglobulin fusion in a tissue-specific manner in pancreatic islets.
    Type: Application
    Filed: October 24, 2012
    Publication date: April 24, 2014
    Applicant: MWM Biomodels GmbH
    Inventors: Eckhard Wolf, Nikolai Klymiuk, Lelia Wolf-van Buerck, Jochen Seissler