Abstract: A physiological response to activity (PRA) during a subject's activities of daily living (ADL) can be used, such as to generate useful diagnostic information about the subject. This can involve using a template, such as an impulse response template. The technique can be used with an implantable or other ambulatory medical monitoring or therapy device, such as a cardiac function management device, or with a local or remote external interface device.

Abstract: Systems and methods for estimating caloric expenditure. The systems can include a physiological sensor to measure a patient's physical activity, and a posture sensor to measure the patient's posture. An estimated caloric expenditure can be calculated based on data from the physiological sensor and the posture sensor. For example, the estimated caloric expenditure can be calculated at least in part based on the posture data. For example, the estimated caloric expenditure can be validated based on the posture data.

Abstract: Systems and methods for estimating caloric expenditure. The systems can include a physiological sensor to measure a patient's physical activity, and a posture sensor to measure the patient's posture. An estimated caloric expenditure can be calculated based on data from the physiological sensor and the posture sensor. For example, the estimated caloric expenditure can be calculated at least in part based on the posture data. For example, the estimated caloric expenditure can be validated based on the posture data.

Abstract: A system includes an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Abstract: Systems and methods for estimating caloric expenditure. The systems can include a physiological sensor to measure a patient's physical activity, and a posture sensor to measure the patient's posture. An estimated caloric expenditure can be calculated based on data from the physiological sensor and the posture sensor. For example, the estimated caloric expenditure can be calculated at least in part based on the posture data. For example, the estimated caloric expenditure can be validated based on the posture data.

Abstract: A physiological response to activity (PRA) during a subject's activities of daily living (ADL) can be used, such as to generate useful diagnostic information about the subject. This can involve using a template, such as an impulse response template. The technique can be used with an implantable or other ambulatory medical monitoring or therapy device, such as a cardiac function management device, or with a local or remote external interface device.

Abstract: This document discusses, among other things, a system including an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Abstract: This document discusses, among other things, a system including an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Abstract: This document discusses, among other things, a system including an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Abstract: An apparatus for determining the volume of liquid in a probe tip of an aspirating or dispensing probe, such as those used in a diagnostic analyzer, includes: two electrodes on opposite sides of the probe tip and the electrodes and liquid form a variable capacitor; a resistor; a voltage source and the electrodes and resistor are in electrical communication in at least one of series, parallel or series and parallel to form an RC circuit; and a microprocessor in electrical communication with the RC circuit for converting an electrical signal to a volume of liquid in the probe tip. In a preferred embodiment, the probe tip is separate from the probe and is adapted to be fitted on the end of a probe for aspirating and dispensing a liquid.

Abstract: This document discusses, among other things, methods of monitoring physiological responses to steady state activity. In an example, a physical activity signal is detected from a human or animal subject using an implantable medical device. A different, other physiological signal is also detected from the subject using the implantable medical device. The physical activity signal is processed to define first and second time periods associated with first and second steady-state physical activity levels of the subject. A first indicator is obtained by combining data from the other physiological signal obtained during the first time period. A second indicator is obtained by combining data from the other physiological signal obtained during the second time period. The first and second indicators are used provide a diagnostic indicator.

Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Abstract: Systems and methods for estimating caloric expenditure. The systems can include a physiological sensor to measure a patient's physical activity, and a posture sensor to measure the patient's posture. An estimated caloric expenditure can be calculated based on data from the physiological sensor and the posture sensor. For example, the estimated caloric expenditure can be calculated at least in part based on the posture data. For example, the estimated caloric expenditure can be validated based on the posture data.

Abstract: An apparatus for determining the volume of liquid in a probe tip of an aspirating or dispensing probe, such as those used in a diagnostic analyzer, includes: two electrodes on opposite sides of the probe tip and the electrodes and liquid form a variable capacitor; a resistor; a voltage source and the electrodes, resistor, and solenoid are in electrical communication in at least one of series, parallel or series and parallel to form an RC circuit; and a microprocessor in electrical communication with the RC circuit for converting an electrical signal to a volume of liquid in the probe tip. In a preferred embodiment, the probe tip is separate from the probe and is adapted to be fitted on the end of a probe for aspirating and dispensing a liquid.