Patents by Inventor Lena Basile

Lena Basile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of IL-12 and the IL-12 receptor positive cell in tissue repair and regeneration
    Patent number: 8846392
    Abstract: The present application relates to stem cells isolated from various sources within the body of a patient or of a healthy donor and identified by the presence of the interleukin 12 (IL-12) receptor. The present application also provides methods for making and for using the stem cells.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: September 30, 2014
    Assignee: Neumedicines, Inc.
    Inventors: Lena A. Basile, Timothy Kirk Gallaher
  • MITIGATION OF CUTANEOUS INJURY WITH IL-12
    Publication number: 20140205561
    Abstract: The present application relates to treatment of cutaneous wounds using IL-12. The methods of the invention result in improved wound closure. The methods comprise treating cutaneous wounds using topical, subcutaneous, and/or intramuscular administration of IL-12.
    Type: Application
    Filed: June 13, 2012
    Publication date: July 24, 2014
    Inventors: Lena A. Basile, Dolph Ellefson, Timothy K. Gallaher
  • USE OF IL-12 TO GENERATE ENDOGENOUS ERYTHROPOIETIN
    Publication number: 20140178335
    Abstract: The present invention relates to the use of exogenous interleukin-12 (IL-12) for increasing endogenous production of erythropoietin.
    Type: Application
    Filed: July 27, 2012
    Publication date: June 26, 2014
    Inventor: Lena A. Basile
  • Method for treating brain cancer using a novel tumor suppressor gene and secreted factor
    Patent number: 8735342
    Abstract: The present invention is directed to methods of using HSS1 (Hematopoietic Signal peptide-containing Secreted 1), HSM1 (Hematopoietic Signal peptide-containing Membrane domain-containing 1), or a combination thereof in the treatment of various cancers, such as brain cancers.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 27, 2014
    Assignee: Neumedicines, Inc.
    Inventor: Lena A. Basile
  • USES OF IL-12 AND THE IL-12 RECEPTOR POSITIVE CELL IN TISSUE REPAIR AND REGENERATION
    Publication number: 20130259828
    Abstract: The present application relates to stem cells isolated from various sources within the body of a patient or of a healthy donor and identified by the presence of the interleukin 12 (IL-12) receptor. The present application also provides methods for making and for using the stem cells.
    Type: Application
    Filed: September 27, 2011
    Publication date: October 3, 2013
    Applicant: NEUMEDICINES, INC.
    Inventors: Lena A. Basile, Timothy Kirk Gallaher
  • IL-12 FOR RADIATION PROTECTION AND RADIATION-INDUCED TOXICITY MITIGATION
    Publication number: 20130243722
    Abstract: Aspects and embodiments of the instant disclosure provide therapeutic methods and compositions comprising interleukin 12 (IL-12) useful for treating radiation-induced damage in a subject. In particular, the instant disclosure provides methods and compositions for radiation protection and/or radiation toxicity mitigation for the treatment of acute radiation syndrome and radiation induced toxicity associated with the treatment of cutaneous T-cell lymphoma.
    Type: Application
    Filed: January 18, 2013
    Publication date: September 19, 2013
    Applicant: NEUMEDICINES INC.
    Inventors: Lena Basile, Timothy K. Gallaher, Dolph D. Ellefson
  • IL-12 FORMULATIONS FOR ENHANCING HEMATOPOIESIS
    Publication number: 20130129674
    Abstract: Provided are formulations for proteins to be injected into mammals. Specifically, formulations for recombinant IL-12 in mice and primates.
    Type: Application
    Filed: May 18, 2011
    Publication date: May 23, 2013
    Inventor: Lena A. Basile
  • METHOD FOR TREATING BRAIN CANCER USING A NOVEL TUMOR SUPPRESSOR GENE AND SECRETED FACTOR
    Publication number: 20130012452
    Abstract: The present invention is directed to methods of using HSS1 (Hematopoietic Signal peptide-containing Secreted 1), HSM1 (Hematopoietic Signal peptide-containing Membrane domain-containing 1), or a combination thereof in the treatment of various cancers, such as brain cancers.
    Type: Application
    Filed: January 27, 2011
    Publication date: January 10, 2013
    Inventors: Lena A. Basile, Timothy Kirk Gallaher
  • USE OF IL-12 TO INCREASE SURVIVAL FOLLOWING ACUTE EXPOSURE TO IONIZING RADIATION
    Publication number: 20120189577
    Abstract: The present invention is directed to methods of increasing survival following exposure to non-therapeutic radiation comprising administration of IL-12.
    Type: Application
    Filed: January 18, 2012
    Publication date: July 26, 2012
    Inventor: Lena A. BASILE