Patents by Inventor Lena Christiansen

Lena Christiansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LONG INDEXED-LINKED READ GENERATION ON TRANSPOSOME BOUND BEADS
    Publication number: 20240018584
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to on bead tagmentation and droplet indexing. Some embodiments include performing co-assays on partitioned beads, including nucleic acid sequencing, indexed PCR, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Application
    Filed: July 26, 2023
    Publication date: January 18, 2024
    Inventors: Lena Christiansen, Frank J. Steemers, Gary Schroth, Jerushah Thomas, Dmitry K. Pokholok
  • METHOD AND COMPOSITIONS FOR PREPARING NUCLEIC ACID LIBRARIES
    Publication number: 20230105642
    Abstract: Embodiments relate to the preparation of nucleic acid libraries. Some embodiments relate to the preparation of normalized nucleic acid libraries, such as libraries in which the amounts of amplified nucleic acids are substantially the same for different amounts of input nucleic acids. Some embodiments relate to preparation of indexed nucleic acid libraries with certain adaptors.
    Type: Application
    Filed: March 29, 2021
    Publication date: April 6, 2023
    Inventors: Lena Christiansen, Dmitry Pokholok, Frank J. Steemers, Rigo Pantoja, Megan Chu, Patrizia lavicoli, Weihua Chang, Jeffrey Dennis Brodin, Eric Vermaas, Jerishah Thomas, Fan Zhang
  • CONTIGUITY PARTICLE FORMATION AND METHODS OF USE
    Publication number: 20220333157
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Application
    Filed: May 16, 2022
    Publication date: October 20, 2022
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • METHODS AND MEANS FOR PREPARING A LIBRARY FOR SEQUENCING
    Publication number: 20220195507
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to assays for selectively controlling enzymatic reactions. Some embodiments relate to methods of inhibiting, reducing, or eliminating secondary DNA (such as mitochondrial DNA) sequencing reads from open chromatic sequencing, whole genome sequencing, or targeted sequencing.
    Type: Application
    Filed: December 13, 2019
    Publication date: June 23, 2022
    Inventors: Frank J. Steemers, Dmitry K. Pokholok, Lena Christiansen
  • Contiguity particle formation and methods of use
    Patent number: 11359226
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: June 14, 2022
    Assignee: ILLUMINA, INC.
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • CONTIGUITY PARTICLE FORMATION AND METHODS OF USE
    Publication number: 20190352591
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Application
    Filed: April 15, 2019
    Publication date: November 21, 2019
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • ANALYSIS SYSTEM FOR ORTHOGONAL ACCESS TO AND TAGGING OF BIOMOLECULES IN CELLULAR COMPARTMENTS
    Publication number: 20190323003
    Abstract: The invention relates to a system and methods for enhancing access to nuclear informational molecules, such as DNA, RNA, and proteins, by analytical biomolecules, such as transposome complexes, by treating nuclei with a nuclear permeability enhancer, and to methods of using nuclear membrane, cell membrane, and external compartmentalization approaches as contiguity preserving elements.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 24, 2019
    Applicant: ILLUMINA, INC.
    Inventors: Ramesh Ramji, Frank J. Steemers, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang