Patents by Inventor Lenard M. Lichtenberger

Lenard M. Lichtenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9687551
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: June 27, 2017
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20160271255
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Application
    Filed: May 2, 2016
    Publication date: September 22, 2016
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. LICHTENBERGER
  • Publication number: 20160220679
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Application
    Filed: April 11, 2016
    Publication date: August 4, 2016
    Inventor: Lenard M. Lichtenberger
  • Patent number: 9351984
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 31, 2016
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Patent number: 9101637
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: August 11, 2015
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20150011507
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Application
    Filed: September 24, 2014
    Publication date: January 8, 2015
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. LICHTENBERGER
  • Patent number: 8911752
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: December 16, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Patent number: 8865187
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: October 21, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20130281405
    Abstract: Aerosolizable compositions of nonsteroidal anti-inflammatory drugs (NSAIDs) in combination with zwitterionic phospholipids in an aqueous carrier are used for treating lung injury (LI), pulmonary inflammation, and/or airway hyper-responsiveness (AHR). Methods for administering the compositions including orally, parenterally, intra-tracheally, and intra-pulmonarily protocols, especially intra-tracheally and intra-pulmonarily protocols, where the PC-NSAID compositions reduce lung injury (LI), pulmonary inflammation, and/or airway hyper-responsiveness (AHR).
    Type: Application
    Filed: April 2, 2013
    Publication date: October 24, 2013
    Inventors: Lenard M. Lichtenberger, Elizabeth J. Dial
  • Patent number: 8252836
    Abstract: A unique composition of a 5-amino salicylic acid (5ASA) and a phospholipid is disclosed for treating Inflammatory Bowel Disease (IBD), where the composition can be a mixture, a molecular association complex or a covalent compound of 5ASA and a reactive phospholipid covalently bonded together via a diazo linkage and to methods for administering the compositions to treat symptoms of IBD.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: August 28, 2012
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20120196887
    Abstract: Compositions comprising one or more rifamycin antibiotics and one or more bile acids, and methods of using the compositions for the treatment of infection.
    Type: Application
    Filed: February 2, 2012
    Publication date: August 2, 2012
    Inventors: Charles DARKOH, Herbert L. DUPONT, Lenard M. LICHTENBERGER, Elizabeth J. Dial
  • Publication number: 20110071118
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Application
    Filed: September 16, 2010
    Publication date: March 24, 2011
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20110065677
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Application
    Filed: September 16, 2010
    Publication date: March 17, 2011
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20110034568
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
    Type: Application
    Filed: September 16, 2010
    Publication date: February 10, 2011
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Patent number: 7838511
    Abstract: Compositions and methods are disclosed for treating, preventing and/or ameliorating the symptoms of cancers such as breast cancer, colon cancer, ovarian cancer, lung cancer, leukemia, skin cancer, prostate cancer, throat cancer, esophageal cancer etc., where the composition includes an associated complex of a nonsteroidal, anti-inflammatory drug (NSAID) and a phospholipid and the method includes administering before or after cancer identification an anti-cancer amount of the compositions.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: November 23, 2010
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Lenard M. Lichtenberger, Elizabeth J. Dial
  • Publication number: 20100184964
    Abstract: A unique composition of a 5-amino salicylic acid (5ASA) and a phospholipid is disclosed for treating Inflammatory Bowel Disease (IBD), where the composition can be a mixture, a molecular association complex or a covalent compound of 5ASA and a reactive phospholipid covalently bonded together via a diazo linkage and to methods for administering the compositions to treat symptoms of IBD.
    Type: Application
    Filed: March 22, 2010
    Publication date: July 22, 2010
    Applicant: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Publication number: 20100173876
    Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
    Type: Application
    Filed: July 30, 2009
    Publication date: July 8, 2010
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Lenard M. Lichtenberger, Shiqiang Tian
  • Patent number: 7700651
    Abstract: A unique composition of a 5-amino salicylic acid (5ASA) and a phospholipid is disclosed for treating Inflammatory Bowel Disease (IBD), where the composition can be a mixture, a molecular association complex or a covalent compound of 5ASA and a reactive phospholipid covalently bonded together via a diazo linkage and to methods for administering the compositions to treat symptoms of IBD.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: April 20, 2010
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Patent number: 7354912
    Abstract: Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: April 8, 2008
    Assignee: Board of Reagents, University of Texas System
    Inventor: Lenard M. Lichtenberger
  • Patent number: 6943155
    Abstract: Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: September 13, 2005
    Inventor: Lenard M. Lichtenberger