Patents by Inventor Lenard Vranckx

Lenard Vranckx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUNCTIONAL CURE OF RETROVIRAL INFECTION
    Publication number: 20210008066
    Abstract: The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.
    Type: Application
    Filed: September 25, 2020
    Publication date: January 14, 2021
    Applicant: Katholieke Universiteit Leuven
    Inventors: Frauke Christ, Zeger Debyser, Rik Gijsbers, Lenard Vranckx
  • Functional cure of retroviral infection
    Patent number: 10806734
    Abstract: The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: October 20, 2020
    Assignee: Katholieke Universiteit Leuven
    Inventors: Frauke Christ, Zeger Debyser, Rik Gijsbers, Lenard Vranckx
  • FUNCTIONAL CURE OF RETROVIRAL INFECTION
    Publication number: 20180071288
    Abstract: The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.
    Type: Application
    Filed: May 9, 2016
    Publication date: March 15, 2018
    Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Frauke Christ, Zeger Debyser, Rik Gijsbers, Lenard Vranckx