Patents by Inventor Leng-Chun Chen

Leng-Chun Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method Of Determining The Viability Of At Least One Cell
    Publication number: 20140363840
    Abstract: This disclosure provides a method of determining the viability of at least one cell via quantification of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H), flavin adenine dinucleotide (FAD), and/or collagen. The method includes the steps of contacting the at least one cell with light having a wavelength of from 700 to 900 nm, using two photon excitation, or from 335 to 400 nm, using one photon excitation, to induce an optical response from the NAD(P)H, FAD, and/or collagen and measuring the optical response. The method also includes the step of quantifying one or more of an amount, spatial localization, and/or time-dependent response of the NAD(P)H, FAD, and/or collagen utilizing the optical response.
    Type: Application
    Filed: July 3, 2014
    Publication date: December 11, 2014
    Inventors: Mary-Ann Mycek, Stephen Feinberg, Cynthia Marcelo, William Lloyd, Leng-Chun Chen, Shiuhang Kuo, Hyungjin Myra Kim
  • Multimodal spectroscopic systems and methods for classifying biological tissue
    Patent number: 8694266
    Abstract: Multimodal optical spectroscopy systems and methods produce a spectroscopic event to obtain spectroscopic response data from biological tissue, either ex vivo or in vivo, and compare the response data with a model configured to correlate the measured response data and the most probable attributes of the tissue, thus facilitating classification of the tissue based on those attributes.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: April 8, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: Mary-Ann Mycek, Malavika Chandra, James Scheiman, Robert H. Wilson, Diane Simeone, Barbara McKenna, Jeremy Taylor, Oliver Lee, Leng-Chun Chen, William Lloyd
  • MULTIMODAL SPECTROSCOPIC SYSTEMS AND METHODS FOR CLASSIFYING BIOLOGICAL TISSUE
    Publication number: 20120245473
    Abstract: Multimodal optical spectroscopy systems and methods produce a spectroscopic event to obtain spectroscopic response data from biological tissue, either ex vivo or in vivo, and compare the response data with a model configured to correlate the measured response data and the most probable attributes of the tissue, thus facilitating classification of the tissue based on those attributes.
    Type: Application
    Filed: May 16, 2012
    Publication date: September 27, 2012
    Inventors: Mary-Ann Mycek, Malavika Chandra, James Scheiman, Robert H. Wilson, Diane Simeone, Barbara McKenna, Jeremy Taylor, Oliver Lee, Leng-Chun Chen, William Lloyd