Abstract: A method of facilitating data-exchange between clinical-trial sites and clinical-trial sponsors, makes use of clinical site profiles and a remote server to manage the clinical-trial site's information. A set of trial-facilitation processes is stored on the remote server and is used to enable a clinical-trial sponsor to manage all the aspects of a clinical trial. To initiate the method of the present invention, the clinical-trial sponsor provides a set of inclusion-exclusion criteria that defines the parameters of a proposed clinical trial. The inclusion-exclusion criteria are then compared to the capabilities of each clinical-trial site profile to identify a list of clinical-trial sites capable of performing the proposed clinical trial. The list of clinical trial sites is then sent to the clinical-trial sponsor and the clinical-trial sponsor is given the opportunity to manage the proposed clinical trial.