Patents by Inventor Lenka Kohutova

Lenka Kohutova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of sulfated polysaccharides, method of preparation, modification and use thereof
    Patent number: 10414832
    Abstract: The invention relates to the preparation and the use of ?,?-unsaturated aldehydes in the structure of sulfated polysaccharides. It concerns the derivatives with a conjugated double bond in the 4th and 5th positions of the galactopyranose part situated in the 6th position with respect to the aldehyde, according to the general structural formula (I) or its hydrated form according to the general structural formula (II). The preparation of these derivatives derives from sulfated polysaccharides containing a galactopyranose ring sulfated in the 4th position that is bound in the polymer chain via ?(1?3) or ?(1?3) O-glycosidic bond. In the described solution, the sulfated polysaccharides undergo a regio- and chemoselective oxidation to form C6-saturated aldehyde, which, via a direct elimination of the sulfate group, provides the ?,?-unsaturated derivative according to the general formula (I) or (II).
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: September 17, 2019
    Assignee: Contipro a.s
    Inventors: Tomas Bobula, Radovan Buffa, Hana Vagnerova, Romana Sulakova, Lucie Wolfova, Lenka Kohutova, Veronika Moravcova, Ondrej Zidek, Pavlina Prochazkova, Vladimir Velebny
  • Derivatives of Sulfated Polysaccharides, Method of Preparation, Modification and Use Thereof
    Publication number: 20180171034
    Abstract: The invention relates to the preparation and the use of ?,?-unsaturated aldehydes in the structure of sulfated polysaccharides. It concerns the derivatives with a conjugated double bond in the 4th and 5th positions of the galactopyranose part situated in the 6th position with respect to the aldehyde, according to the general structural formula (I) or its hydrated form according to the general structural formula (II). The preparation of these derivatives derives from sulfated polysaccharides containing a galactopyranose ring sulfated in the 4th position that is bound in the polymer chain via ?(1?3) or ?(1?3) O-glycosidic bond. In the described solution, the sulfated polysaccharides undergo a regio- and chemoselective oxidation to form C6-saturated aldehyde, which, via a direct elimination of the sulfate group, provides the ?,?-unsaturated derivative according to the general formula (I) or (II).
    Type: Application
    Filed: June 24, 2016
    Publication date: June 21, 2018
    Inventors: Tomas Bobula, Radovan Buffa, Hana Vagnerova, Romana Sulakova, Lucie Wolfova, Lenka Kohutova, Veronika Moravcova, Ondrej Zidek, Pavlina Prochazkova, Vladimir Velebny