Abstract: A method for manufacturing a flexible surface element with at least one thermoplastic, thermosetting and/or elastomeric wear layer is provided. The method includes introducing expandable hollow microspheres into the wear layer and/or a functional layer, applying at least one pressure-resistant layer detachably to the wear layer, and subsequently heating at least one section of the surface element to be treated by a thermal energy supply to a temperature within an expansion temperature range of the hollow microspheres, so that at least the hollow microspheres contained in the section to be treated are at least partially expanded and/or further expanded. Expansion of the hollow microspheres is limited by pressure-resistant properties of the pressure-resistant layer. The method further includes removing the pressure-resistant layer from the wear layer at least sectionally.

Abstract: The present invention relates to compounds of Formula (I), combinations and use thereof for disease therapy, or pharmaceutically acceptable salt or solvate thereof, including all tautomers, stereoismers and polymorphs thereof, which are iGluR receptor inhibitors, and hence are useful in the treatment of psychiatric diseases or neurological disorders or a disease or disorder associated with abnormal activities of iGluR receptors.