Abstract: An apparatus for filling a pouch type package with a liquid product, comprising a plurality of stations arranged to consecutively receive and handle the pouch type package, the plurality of stations comprising a filling station for filling the product compartment with the liquid product, a sealing station for sealing the product compartment and comprising a first sealing member arranged to provide the pouch type package with a first seal closing the filling duct, a gas filling station arranged to introduce gas into the handle compartment, and a transfer unit comprising a gripping member for retrieving the package from the gas filling station and transferring it to a neighboring down-stream situated station. A gas sealing unit (36) integrated in the gripping member of the transfer unit, the gas sealing unit (36) comprising a second sealing member (37) arranged to provide the pouch type package with a second seal entrapping gas introduced into the handle compartment.

Abstract: An apparatus for filling a pouch type package with a liquid product, comprising a plurality of stations arranged to consecutively receive and handle the pouch type package, the plurality of stations comprising a filling station for filling the product compartment with the liquid product, a sealing station for sealing the product compartment and comprising a first sealing member arranged to provide the pouch type package with a first seal closing the filling duct, a gas filling station arranged to introduce gas into the handle compartment, and a transfer unit comprising a gripping member for retrieving the package from the gas filling station and transferring it to a neighboring down-stream situated station. A gas sealing unit (36) integrated in the gripping member of the transfer unit, the gas sealing unit (36) comprising a second sealing member (37) arranged to provide the pouch type package with a second seal entrapping gas introduced into the handle compartment.

Abstract: In accordance with the present inventive concept, there is provided a method for sealing a flexible package of collapsible type. The method comprises providing a first seal extending transverse a filling channel of the flexible package and providing a second seal extending transverse a filling channel of the flexible package. Said second seal overlaps said first seal such that a combined seal is provided comprising a top portion formed solely by a first sealing unit, an intermediate portion formed by the first and a second sealing unit, and a bottom portion formed solely by the second sealing unit.

Abstract: A device for filling a container of a collapsible type with a product in the form of powder or liquid, the container having a compartment which is defined by flexible walls and whose volume is dependent on the relative position of the walls and which communicates with the surroundings through a filling duct of the container. The device comprises a filling tube (2) with an end portion (5), which is insertable into the filling duct of the container to supply a product to the compartment of the container through the filling tube 2.

Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.

Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.

Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.

Abstract: A packaging unit (1) for continuously producing aseptic sealed packages (2), containing a pourable food product, from a tube (14) of packaging material filled with the food product; the unit (1) has a first and second chain conveyor (10, 11) respectively having a number of jaws (12) and a number of counter-jaws (13), which cooperate with and grip the tube (14) to heat-seal the tube at successive cross sections (54) by means of induction heating elements (29) on the jaws (12); and each jaw (12) has a pair of movable elements (60) for interacting with and correcting supply of the tube (14), and the travel of which is controlled by a control assembly (95) in response to a signal (107) related to the position of designs (31) on the packaging material.

Abstract: A unit (1) for feeding a succession of sealed packages (2) containing pourable food products along a first path (P) from a supply station (4) to an output station (5), and for simultaneously tipping the packages (2) from a supply position in which the packages (2) are positioned with a respective axis (A) oriented in a first direction (B), to an output position in which the respective axis (A) is oriented in a second direction (C) perpendicular to the first direction (B); the unit (1) having a number of push arms (15) for feeding respective packages (2) along the first path (P), an actuating member (14) for moving the arms (15) along an endless second path (S) having a portion (S.sub.

Abstract: A packaging unit (1) for continuously producing aseptic sealed packages (2), containing a pourable food product, from a tube (14) of packaging material filled with the food product; the unit (1) has a first and second chain conveyor (10, 11) respectively having a number of jaws (12) and a number of counter-jaws (13), which interact with and grip the tube (14) to heat-seal the tube at successive cross sections by means of induction heating elements (29) on the jaws (12); and each counter-jaw (13) has a push bar (35) fitted to a main body (20) of the counter-jaw via the interposition of springs (75) defining the gripping pressure exerted on the packaging material.