Patents by Inventor Leo Chou

Leo Chou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOSYNTHETIC MODULES
    Publication number: 20190083522
    Abstract: The present disclosure provides, in some aspects, nucleic acid-based biosynthetic modules for the production of ribonucleic acid (RNA) and other biopolymers.
    Type: Application
    Filed: March 9, 2017
    Publication date: March 21, 2019
    Applicants: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.
    Inventors: William M. Shih, Leo Chou, Rasmus Sorensen, Jaeseung Hahn
  • Synthesis of fluorescent noble metal nanoparticles
    Patent number: 9395371
    Abstract: A process for the production of fluorescent nanoparticles selected from noble metal or silica nanoparticles. Noble metals or silica nanoparticles provide a platform to which fluorophores and other detection molecules can be added. The fluorescent nanoparticles can be used as regents, diagnostic assays and in the tracking or targeting of tumors.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: July 19, 2016
    Inventors: Warren Chan, Steven Perrault, Leo Chou
  • SYNTHESIS OF FLUORESCENT NOBLE METAL NANOPARTICLES
    Publication number: 20130183665
    Abstract: A process for the production of fluorescent nanoparticles selected from noble metal, silica or polymer nanoparticles which comprises: 1. A process for the production of fluorescent nanoparticles selected from noble metal or silica nanoparticles which comprises: (1) providing a platform of nanoparticles; (2) covering the surfaces of the nanoparticles to saturation with thiol-terminated polymers by one of the following methods: 1. mixing the nanoparticles with methoxy-(polyethylene glycol)-thiol and biotin-(polyethylene glycol)-thiol; 2. mixing the nanoparticles with fluorescently-labeled methoxy-(polyethylene glycol)-thiol and/or biotin-(polyethylene glycol)-thiol 3. coordinating thiol and biotin thiol to the surfaces of the nanoparticles by a non-covalent bond; and 4.
    Type: Application
    Filed: September 23, 2011
    Publication date: July 18, 2013
    Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Warren Chan, Steven Perrault, Leo Chou