Patents by Inventor Leo Edmond Otterbein

Leo Edmond Otterbein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF
    Publication number: 20160137679
    Abstract: Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.
    Type: Application
    Filed: September 8, 2015
    Publication date: May 19, 2016
    Applicant: Alfama, Inc.
    Inventors: Walter Anton Blättler, Carlos J.R.C. Romão, Sandra Sofia Pereira Rodrigues, Lukas Adrian Kromer, Leo Edmond Otterbein, David John Gallo
  • Carbon monoxide releasing molecules and uses thereof
    Patent number: 9163044
    Abstract: Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: October 20, 2015
    Assignee: Alfama, Inc.
    Inventors: Walter Anton Blättler, Carlos J. R. C. Romão, Sandra Sofia Pereira Rodrigues, Lukas Adrian Kromer, Leo Edmond Otterbein, David John Gallo
  • CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF
    Publication number: 20140142176
    Abstract: Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.
    Type: Application
    Filed: April 19, 2012
    Publication date: May 22, 2014
    Applicant: ALFAMA, INC.
    Inventors: Walter Anton Blättler, Carlos J.R.C. Romäo, Sandra Sofia Pereira, Lukas Adrian Kromer, Leo Edmond Otterbein, David John Gallo