Patents by Inventor Leo Edwin DEELMAN

Leo Edwin DEELMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAMAGE
    Publication number: 20210024485
    Abstract: The present invention relates to compounds for prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially to compounds for prophylaxis or treatment of diabetic kidney damage. Specifically, the present invention relates to 6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6-dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially diabetic kidney organ damage.
    Type: Application
    Filed: June 8, 2020
    Publication date: January 28, 2021
    Inventors: Adrianus Cornelis van der GRAAF, Robert Henk HENNING, Leo Edwin DEELMAN, Gerrit Jan Willem EUVERINK
  • Compound for the prophylaxis or treatment of organ damage
    Patent number: 10676452
    Abstract: The present invention relates to compounds for prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially to compounds for prophylaxis or treatment of diabetic kidney damage. Specifically, the present invention relates to 6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6-dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially diabetic kidney organ damage.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: June 9, 2020
    Assignee: Sulfateq B.V.
    Inventors: Adrianus Cornelis Van Der Graaf, Robert Henk Henning, Leo Edwin Deelman, Gerrit Jan Willem Euverink
  • COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAGAMAGE
    Publication number: 20180170892
    Abstract: The present invention relates to compounds for prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially to compounds for prophylaxis or treatment of diabetic kidney damage. Specifically, the present invention relates to 6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6-dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially diabetic kidney organ damage.
    Type: Application
    Filed: May 12, 2016
    Publication date: June 21, 2018
    Applicant: Sulfateq B.V.
    Inventors: Adrianus Cornelis VAN DER GRAAF, Robert Henk HENNING, Leo Edwin DEELMAN, Gerrit Jan Willem EUVERINK