Patents by Inventor Leo Gu

Leo Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULE WITH SUBSTRATE RECESS FOR CONDUCTIVE-BONDING COMPONENT
    Publication number: 20240030093
    Abstract: In one general aspect, a method can include forming a recess and a mesa in a metal layer associated with a substrate, and disposing a first portion of a conductive-bonding component on the mesa and a second portion of the conductive-bonding component in the recess. The method can include disposing a semiconductor component on the conductive-bonding component such that the second portion of the conductive-bonding component is disposed between an edge of the semiconductor component and a bottom surface of the recess.
    Type: Application
    Filed: October 2, 2023
    Publication date: January 25, 2024
    Applicant: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Leo GU, Sixin JI, Jie CHANG, Keunhyuk LEE, Yong LIU
  • Compounds, Compositions and Methods for the Treatment of CREB-dependent Diseases
    Publication number: 20230416191
    Abstract: The present invention provides bicyclic compounds, pharmaceutical formulations of the compounds, and methods of using the formulations in the treatment or prevention of cancers mediated by cyclic-AMP (cAMP) response element binding protein (CREB), such as leukemias, breast cancer, lung cancer, and prostate cancer.
    Type: Application
    Filed: June 22, 2022
    Publication date: December 28, 2023
    Inventors: Leo Gu, Narinder S. Banait
  • Module with substrate recess for conductive-bonding component
    Patent number: 11776871
    Abstract: In one general aspect, an apparatus can include a semiconductor component, a substrate including a recess, and a conductive-bonding component. The conductive-bonding component is disposed between the semiconductor component and the substrate. The conductive-bonding component has a first thickness between a bottom of the recess and a bottom surface of the semiconductor component greater than a second thickness between the top of the substrate and the bottom surface of the semiconductor component.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: October 3, 2023
    Assignee: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Leo Gu, Sixin Ji, Jie Chang, Keunhyuk Lee, Yong Liu
  • MODULE WITH SUBSTRATE RECESS FOR CONDUCTIVE-BONDING COMPONENT
    Publication number: 20220189848
    Abstract: In one general aspect, an apparatus can include a semiconductor component, a substrate including a recess, and a conductive-bonding component. The conductive-bonding component is disposed between the semiconductor component and the substrate. The conductive-bonding component has a first thickness between a bottom of the recess and a bottom surface of the semiconductor component greater than a second thickness between the top of the substrate and the bottom surface of the semiconductor component.
    Type: Application
    Filed: December 15, 2020
    Publication date: June 16, 2022
    Applicant: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Leo GU, Sixin JI, Jie CHANG, Keunhyuk LEE, Yong LIU
  • PHARMACEUTICAL FORMULATIONS
    Publication number: 20210401759
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension. Described herein are liquid formulations which deliver an ascomycin. The liquid formulation can be placed in a soft gelatin capsule.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Inventors: Narinder S. BANAIT, Leo GU
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF PULMONARY HYPERTENSION
    Publication number: 20210338642
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension.
    Type: Application
    Filed: July 12, 2021
    Publication date: November 4, 2021
    Inventors: Narinder S. BANAIT, Leo GU
  • COMBINATION THERAPY FOR PULMONARY HYPERTENSION
    Publication number: 20210267951
    Abstract: The present invention provides compositions and methods for the treatment of pulmonary hypertension using combination therapy. The combination therapy comprises a compound that increases BMPR2 signaling (BMPR2 activator) in combination with at least one other agent for the treatment of pulmonary hypertension. In certain aspects, the BMPR2 activator can be tacrolimus or a pharmaceutically acceptable solvate, salt, or prodrug thereof.
    Type: Application
    Filed: May 11, 2021
    Publication date: September 2, 2021
    Inventors: Leo Gu, Paul C. Nakagaki, Narinder S. Banait
  • PHARMACEUTICAL FORMULATIONS
    Publication number: 20210113477
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension. Described herein are liquid formulations which deliver an ascomycin. The liquid formulation can be placed in a soft gelatin capsule.
    Type: Application
    Filed: June 5, 2020
    Publication date: April 22, 2021
    Inventors: Narinder S. BANAIT, Leo GU
  • COMBINATION THERAPY FOR PULMONARY HYPERTENSION
    Publication number: 20200069658
    Abstract: The present invention provides compositions and methods for the treatment of pulmonary hypertension using combination therapy. The combination therapy comprises a compound that increases BMPR2 signaling (BMPR2 activator) in combination with at least one other agent for the treatment of pulmonary hypertension. In certain aspects, the BMPR2 activator can be tacrolimus or a pharmaceutically acceptable solvate, salt, or prodrug thereof.
    Type: Application
    Filed: April 11, 2019
    Publication date: March 5, 2020
    Inventors: Leo GU, Paul C. NAKAGAKI, Narinder S. BANAIT
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF PULMONARY HYPERTENSION
    Publication number: 20200054613
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension.
    Type: Application
    Filed: March 21, 2019
    Publication date: February 20, 2020
    Inventors: Narinder S. BANAIT, Leo GU
  • PHARMACEUTICAL FORMULATIONS
    Publication number: 20190350864
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension. Described herein are liquid formulations which deliver an ascomycin. The liquid formulation can be placed in a soft gelatin capsule.
    Type: Application
    Filed: December 14, 2018
    Publication date: November 21, 2019
    Inventors: Narinder S. BANAIT, Leo GU
  • COMBINATION THERAPY FOR PULMONARY HYPERTENSION
    Publication number: 20180325875
    Abstract: The present invention provides compositions and methods for the treatment of pulmonary hypertension using combination therapy. The combination therapy comprises a compound that increases BMPR2 signaling (BMPR2 activator) in combination with at least one other agent for the treatment of pulmonary hypertension. In certain aspects, the BMPR2 activator can be tacrolimus or a pharmaceutically acceptable solvate, salt, or prodrug thereof.
    Type: Application
    Filed: January 8, 2016
    Publication date: November 15, 2018
    Inventors: Leo GU, Paul C. NAKAGAKI, Narinder S. BANAIT
  • PHARMACEUTICAL FORMULATIONS
    Publication number: 20180243224
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension. Described herein are liquid formulations which deliver an ascomycin. The liquid formulation can be placed in a soft gelatin capsule.
    Type: Application
    Filed: August 16, 2016
    Publication date: August 30, 2018
    Inventors: Narinder S. BANAIT, Leo GU
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF PULMONARY HYPERTENSION
    Publication number: 20180125828
    Abstract: The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension.
    Type: Application
    Filed: May 4, 2016
    Publication date: May 10, 2018
    Inventors: Narinder S. BANAIT, Leo GU
  • Pharmaceutical formulations of nerve growth factor
    Patent number: 6277828
    Abstract: Stable, aqueous pharmaceutical formulations of human nerve growth factor (NGF) in aqueous isotonic solutions, buffered to maintain the pH from about 4.5 to about 6.0, and optionally containing a carrier such as human serum albumin are provided. Also provided are aqueous NGF formulations suitable for lyophilization and subsequent reconstitution in which rhNGF is admixed with sugars, optionally HSA, and buffer. The formulations are useful for the treatment of Alzheimer's disease and other neuronal disorders.
    Type: Grant
    Filed: August 20, 1993
    Date of Patent: August 21, 2001
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Victoria M. Knepp, Deborah M. Lidgate, Richard Maskiewicz, Leo Gu
  • Cyclic peptides having broad spectrum antimicrobial activity
    Patent number: 5916872
    Abstract: The present invention provides cyclic peptides having broad spectrum antimicrobial activity. The peptides exhibit improved efficacy, bioavailability and/or serum half-life as compared with non-cyclized analogues.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: June 29, 1999
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Conway Chang, Leo Gu, Jie Chen
  • Mycophenolate mofetil high dose oral suspensions
    Patent number: 5688529
    Abstract: High dose, dry granulations or powder blends and aqueous oral suspensions of mycophenolate mofetil or mycophenolic acid, contain: active compound (7.5-30%), suspending/viscosity agent, sweetener, flavor, buffer (to a pH of 5-7.5), and optionally contain flavor enhancer, wetting agent, antimicrobial agent and color.
    Type: Grant
    Filed: March 29, 1995
    Date of Patent: November 18, 1997
    Assignee: Syntex (U.S.A) Inc.
    Inventors: Deborah Marilyn Lidgate, Li-hua Wang-Kessler, Bindu Joshi, Sayee Gojanan Hegde, Leo Gu