Abstract: The invention relates to a methods, compositions and kits for treating hyperglycemia and related disorders, such as type 2 diabetes mellitus, impaired glucose tolerance, diabetic retinopathy, diabetic nephropathy and diabetic neuropathy, and to methods, compositions and kits for treating erectile dysfunction. The methods comprise administering an inhibitor of fatty acid oxidation to a subject in need thereof. In some embodiments, trimetazidine and metformin or a phosphodiesterase 5 inhibitor are administered.

Abstract: A method for assaying lipoprotein (a) in a liquid sample containing other lipoproteins, and a assay device for use in the method are disclosed. In the method, the liquid is contacted with a solid-support reagent containing lectin attached to a solid support, under conditions effective to bind of lipoprotein (a) to the support-bound lectin. After removing unbound lipoproteins, the amount of lipoprotein (a) bound to the support is assayed. In one embodiment, the method and assay device are designed for assaying cholesterol associated with lipoprotein (a).