Patents by Inventor Leo K. Mathur

Leo K. Mathur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aldosterone antagonist composition for release during aldosterone acrophase
    Publication number: 20020132001
    Abstract: A pharmaceutical composition is provided for administration to a subject mammal such as a human exhibiting a diurnal cycle of plasma aldosterone concentration, the composition comprising a delayed-release formulation of an aldosterone antagonist drug, e.g., eplerenone, in a therapeutically effective amount. The delayed-release formulation, when administered about 6 hours to about 12 hours prior to the acrophase, results in a profile of plasma drug concentration that corresponds substantially to the diurnal cycle of plasma aldosterone concentration.
    Type: Application
    Filed: May 11, 2001
    Publication date: September 19, 2002
    Inventors: Susan M. Garthwaite, Leo K. Mathur
  • Stabilized pharmaceutical admixture composition
    Patent number: 5015481
    Abstract: A stabilized pharmaceutical composition which is an admixture of an NSAID selected from diclofenac and piroxicam, a prostaglandin and hydroxypropyl methylcellulose for maintaining the prostaglandin in a therapeutically effective amount without negatively affecting the therapeutic activity of the NSAID.
    Type: Grant
    Filed: May 3, 1990
    Date of Patent: May 14, 1991
    Assignee: G. D. Searle & Co.
    Inventors: Michel Franz, Michel Jans, Leo K. Mathur, Kamlesh B. Shah, James E. Truelove