Patents by Inventor Leo L. Chan

Leo L. Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for cell imaging, analysis and measurement
    Patent number: 11911764
    Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: February 27, 2024
    Assignee: Nexcelom Bioscience LLC
    Inventors: Peter Y. Li, Jean Qiu, Leo L. Chan, Justin R. Hascup, Timothy F. Smith, Todd R. Sobolewski, Nicholas N. Shaw
  • Yeast concentration and viability measurement
    Patent number: 11473121
    Abstract: The invention generally relates to analyzing yeast viability. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring viability and concentration of yeast cells.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: October 18, 2022
    Assignee: NEXCELOM BIOSCIENCE LLC
    Inventor: Leo L. Chan
  • SYSTEMS AND METHODS FOR CELL COUNT MEASUREMENTS
    Publication number: 20220307966
    Abstract: The invention provides novel sample chambers, units and multi-well plates, and systems and methods thereof, for built-in measurement assurance of cell counting methods and calibrated and/or quality-assured measurement and analysis of diverse types of biological cells, e.g., cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Application
    Filed: September 2, 2020
    Publication date: September 29, 2022
    Inventors: Jean Qiu, Peter Y. Li, Leo L. Chan, Jordan Bell
  • SYSTEM AND METHOD FOR CELL IMAGING, ANALYSIS AND MEASUREMENT
    Publication number: 20210069696
    Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
    Type: Application
    Filed: February 21, 2019
    Publication date: March 11, 2021
    Inventors: Peter Y. Li, Jean Qiu, Leo L. Chan, Justin R. Hascup, Timothy F. Smith, Todd R. Sobolewski, Nicholas N. Shaw
  • AUTOMATED YEAST BUDDING MEASUREMENT
    Publication number: 20200385775
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: August 22, 2020
    Publication date: December 10, 2020
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • METHODS FOR CELL COUNT AND VIABILITY MEASUREMENTS
    Publication number: 20180128717
    Abstract: The invention provides a method for accurate, efficient and high-throughout measurement of cell viability of diverse biological samples.
    Type: Application
    Filed: June 1, 2016
    Publication date: May 10, 2018
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Olivier Déry, Sarah Kessel, Timothy Smith
  • AUTOMATED YEAST BUDDING MEASUREMENT
    Publication number: 20180119195
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 3, 2018
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • Internal focus reference beads for imaging cytometry
    Patent number: 9933415
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: April 3, 2018
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Systems and methods for counting cells and biomolecules
    Patent number: 9329130
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention relates to systems and methods for imaging, measuring, counting, analyzing, and monitoring microscopic particles such as cells and biological molecules in solution samples.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: May 3, 2016
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Peter Li
  • INTERNAL FOCUS REFERENCE BEADS FOR IMAGING CYTOMETRY
    Publication number: 20160025710
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 28, 2016
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • Cell counting and sample chamber and methods of fabrication
    Patent number: 9186843
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: November 17, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu
  • AUTOMATED YEAST BUDDING MEASUREMENT
    Publication number: 20150232906
    Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
    Type: Application
    Filed: October 9, 2013
    Publication date: August 20, 2015
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan
  • Internal focus reference beads for imaging cytometry
    Patent number: 9075790
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: July 7, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • CELL COUNTING AND SAMPLE CHAMBER AND METHODS OF FABRICATION
    Publication number: 20150183153
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Application
    Filed: December 31, 2014
    Publication date: July 2, 2015
    Inventors: Leo L. Chan, Jean Qiu
  • Cell counting and sample chamber and methods of fabrication
    Patent number: 8928876
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: January 6, 2015
    Assignee: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu
  • YEAST CONCENTRATION AND VIABILITY MEASUREMENT
    Publication number: 20140024074
    Abstract: The invention generally relates to analyzing yeast viability. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring viability and concentration of yeast cells.
    Type: Application
    Filed: June 6, 2011
    Publication date: January 23, 2014
    Applicant: NEXCELOM BIOSCIENCE LLC
    Inventor: Leo L. Chan
  • INTERNAL FOCUS REFERENCE BEADS FOR IMAGING CYTOMETRY
    Publication number: 20130336567
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
    Type: Application
    Filed: October 20, 2011
    Publication date: December 19, 2013
    Applicant: Nexcelom Bioscience LLC
    Inventors: Leo L. Chan, Jean Qiu, Peter Li, Kevin Flanagan, Timothy Smith
  • CELL COUNTING AND SAMPLE CHAMBER AND METHODS OF FABRICATION
    Publication number: 20130120747
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 16, 2013
    Inventors: Leo L. Chan, Jean Qiu
  • SYSTEMS AND METHODS FOR COUNTING CELLS AND BIOMOLECULES
    Publication number: 20130099120
    Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention relates to systems and methods for imaging, measuring, counting, analyzing, and monitoring microscopic particles such as cells and biological molecules in solution samples.
    Type: Application
    Filed: January 11, 2011
    Publication date: April 25, 2013
    Inventors: Leo L. Chan, Peter Li