Patents by Inventor Leo L. Wang

Leo L. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogel Compositions
    Publication number: 20210338821
    Abstract: Provided are compositions comprising a hydrogel formed from a cyclodextrin-modified branched polyethyleneimine and an adamantane-modified, eight-arm polyethyelene glycol. The hydrogel may contain an active agent, and can provide sustained release the active agent. Beneficial delivery characteristics may result from electrostatic or lipophilic interactions between the active agent and the hydrogel. Delivery of valproic acid from the present compositions can provide treatment following surgical resection of glioblastoma brain tumors.
    Type: Application
    Filed: July 12, 2021
    Publication date: November 4, 2021
    Inventors: Kalil G Abdullah, Leo L Wang, Jason Alan Burdick
  • INJECTABLE HYDROGELS FOR LOCAL DELIVERY TO THE HEART
    Publication number: 20210322652
    Abstract: The invention concerns methods of delivering a hydrogel to the heart, comprising: introducing a hydrogel composition into a subject, said hydrogel comprising components mixed prior to introduction; the introducing being performed such that the hydrogel composition resides between the epicardium and the pericardium of the subject. In some embodiments, the injection is performed using a syringe or catheter.
    Type: Application
    Filed: August 30, 2019
    Publication date: October 21, 2021
    Inventors: Brendan Patrick PURCELL, Jason Alan BURDICK, Leo L. WANG
  • Hydrogel Compositions
    Publication number: 20190290769
    Abstract: Provided are compositions comprising a hydrogel formed from a cyclodextrin-modified branched polyethyleneimine and an adamantane-modified, eight-arm polyethyelene glycol. The hydrogel may contain an active agent, and can provide sustained release the active agent. Beneficial delivery characteristics may result from electrostatic or lipophilic interactions between the active agent and the hydrogel. Delivery of valproic acid from the present compositions can provide treatment following surgical resection of glioblastoma brain tumors.
    Type: Application
    Filed: March 25, 2019
    Publication date: September 26, 2019
    Inventors: Kalil G. Abdullah, Leo L. Wang, Jason Alan Burdick