Patents by Inventor Leo M. Sreebny

Leo M. Sreebny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5510122
    Abstract: The preparation of a saliva composition substantially viable for therapeutic use in saliva-deficient individuals involves exogenously treating saliva to inactivate microorganisms by contacting with chlorhexidine or ionizing radiation. Pharmaceutically active agents may be added to the saliva composition.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: April 23, 1996
    Assignee: The Research Foundation of State University of New York
    Inventors: Leo M. Sreebny, Steven S. Schwartz, Allen G. Meek
  • Patent number: 5078129
    Abstract: A dispenser for an aqueous sialogogue for the mouth comprises:a) a reservoir for the aqueous sialogogue solution;b) passage means leading from the reservoir to a spray head; andc) a plurality of orifices in the spray head, whereby actuating the spray head causes a plurality of streams to be directed to those regions of the mouth most dry in a reniform pattern.Preferably a metered amount of sialogogue is delivered by an actuating means selected from the group consisting of a hand-activating spray pump, a bulb-activated spray pump or an aerosol propellant.The sialogogue solution comprises:a) from about 2 to about 3 wgt % of food-grade organic acidulant;b) a food-grade sweetener benign to stomic microflora; andc) a saturated calcium phosphate solution, whereby the production of human saliva is promoted in situ without corrosion, infection, or dissolution of human teeth.
    Type: Grant
    Filed: March 8, 1990
    Date of Patent: January 7, 1992
    Assignee: Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Leo M. Sreebny
  • Patent number: 4820506
    Abstract: An aqueous liquid for promoting the production of human saliva in situ comprises:(a) about 2 to 3 wgt percent organic acidulent such as citric, malic, or ascorbic acid;(b) about 0.5 to 2.5 wgt percent of a natural, food-grade sweetener such as fructose or 0.05 to 0.5 wgt percent of a synthetic sweetener such as aspartame or saccharin; and(c) a saturated calcium phosphate solution.The preferred form of the aqueous liquid is a metered, hand-actuated, aerosol spray of about 0.15 ml. per actuation.By employing the aqueous liquid of the invention the production of saliva is tripled, thus alleviating the many symptoms of xerostomia no matter what its cause.
    Type: Grant
    Filed: May 1, 1987
    Date of Patent: April 11, 1989
    Assignee: Research Foundation, State University of New York
    Inventors: Israel Kleinberg, Leo M. Sreebny
  • Patent number: 4768238
    Abstract: This patent relates to a bifurcated vessel for the collection of saliva comprising:(a) a receptacle open at one end and divided into two chambers for holding liquid;(b) an open edge portion angularly disposed integral with one of said chambers to constitute a flared funnel to said chamber; and(c) a second open edge portion angularly disposed to and integral with the other of said two chambers to constitute a flared funnel.
    Type: Grant
    Filed: May 4, 1987
    Date of Patent: September 6, 1988
    Assignee: Interstate Drug Exchange
    Inventors: Israel Kleinberg, Leo M. Sreebny