Patents by Inventor Leo Rubin

Leo Rubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050059574
    Abstract: This invention provides a stable composition containing T3, serum albumin and water, wherein the T3 has a half-life of at least five days, particularly at neutral pH. This invention further provides a method for emergency treatment of a patient with cardiac arrest and with cardiac electrical standstill to restore effective cardiac function, comprising administering to the patient a therapeutically effective amount of the stable composition.
    Type: Application
    Filed: November 30, 2001
    Publication date: March 17, 2005
    Inventors: Irwin Klein, Kaie Ojamaa, Leo Rubin
  • Publication number: 20040186521
    Abstract: Methods and apparatus for treating fibrillation utilize biphasic waveforms. A cardiac stimulator includes a defibrillation circuit that uses a pulse width modulated capacitive discharge to generate various biphasic waveforms, one or more of which may be delivered to the heart to treat the fibrillation.
    Type: Application
    Filed: March 26, 2004
    Publication date: September 23, 2004
    Applicant: Intermedics Inc.
    Inventors: Leo Rubin, Chris A. Bonnerup, Edward A. Schroeppel
  • Patent number: 6757561
    Abstract: Methods and apparatus for treating fibrillation utilize biphasic waveforms. A cardiac stimulator includes a defibrillation circuit that uses a pulse width modulated capacitive discharge to generate various biphasic waveforms, one or more of which may be delivered to the heart to treat the fibrillation.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: June 29, 2004
    Assignee: Intermedics Inc.
    Inventors: Leo Rubin, Christopher A. Bonnerup, Edward A. Schroeppel
  • Publication number: 20040030365
    Abstract: The present invention relates generally to a medical device for monitoring and controlling arrhythmias, and for restoring functions of a fibrillating heart in a subject by therapies directed by a physician via two-way communication between the device and the physician, comprising (a) an implant; and (b) a wearable unit comprising a programmer, and a position-locating module; (c) a first interface for communication between the implant and the programmer, and (d) a second interface for two-way communication between a physician in an emergency team and the programmer through the position-locating module, wherein data on the location of the subject and the subject's heart conditions are sent to the physician for evaluation and instructions for therapy are sent from the physician to the programmer.
    Type: Application
    Filed: August 5, 2003
    Publication date: February 12, 2004
    Inventor: Leo Rubin
  • Publication number: 20020035382
    Abstract: Methods and apparatus for treating fibrillation utilize biphasic waveforms. A cardiac stimulator includes a defibrillation circuit that uses a pulse width modulated capacitive discharge to generate various biphasic waveforms, one or more of which may be delivered to the heart to treat the fibrillation.
    Type: Application
    Filed: September 28, 2001
    Publication date: March 21, 2002
    Applicant: Intermedics Inc.
    Inventors: Leo Rubin, Christopher A. Bonnerup, Edward A. Schroeppel
  • Patent number: 6298266
    Abstract: Methods and apparatus for treating fibrillation utilize biphasic waveforms. A cardiac stimulator includes a defibrillation circuit that uses a pulse width modulated capacitive discharge to generate various biphasic waveforms, one or more of which may be delivered to the heart to treat the fibrillation.
    Type: Grant
    Filed: August 10, 1999
    Date of Patent: October 2, 2001
    Assignee: Intermedics Inc.
    Inventors: Leo Rubin, Christopher A. Bonnerup, Edward A. Schroeppel
  • Patent number: 5910124
    Abstract: Cardiac ventricular assist apparatus adapted to be placed by insertion through an incision in the wall of the upper abdomen below the rib cage and an incision in the inferior aspect of the pericardium proximate the heart apex comprises a flexible bladder assembly that adapted to be passed through the incision in the pericardium to a position between the pericardial sac and the epicardium. The bladder assembly is of a size such and shape such as to be engageable with a substantial portion of the outer surface of the left ventricle of a heart. The bladder assembly includes a distensible pumping bladder that is attached to a tube through which a gas can be introduced into it to compress the left ventricle and withdrawn from it to allow the ventricle to fill and a non-distensible retaining bladder, which is substantially coextensive with the pumping bladder and receives a packed body of particulate material.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: June 8, 1999
    Assignee: Cardiassist Incorporated
    Inventor: Leo Rubin
  • Patent number: 5707336
    Abstract: Cardiac ventricular assist apparatus adapted to be placed by insertion through an incision in the wall of the upper abdomen below the rib cage and an incision in the inferior aspect of the pericardium proximate the heart apex comprises a distensible flexible bladder adapted to be passed through the incision in the pericardium to a position between the pericardial sac and the epicardium. The bladder is of a size such and shape such as to be engageable with a substantial portion of the outer surface of the left ventricle of a heart and is attached to a tube through which a gas can be introduced into it to compress the left ventricle and withdrawn from it to allow the ventricle to fill. A non-dietensible tube joined to the distal edge of the bladder is connected to a source of a fluid by which it can be inflated after insertion of the bladder to deploy the distal edge of the bladder from a collapsed condition in which it is emplaced within the pericardium to an extended condition partly encircling the heart.
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: January 13, 1998
    Assignee: Cardassist Incorporated
    Inventor: Leo Rubin
  • Patent number: 5476502
    Abstract: A defibrillator and demand pacer catheter is defined by a flexible, electrically nonconductive probe having an electrically conductive pathway longitudinally disposed therein. Attached to one end of the probe is a defibrillator electrode capable of anchoring the probe to the septum of a heart and of transmitting from said conductive pathway directly to the interior of the septum a portion of an electrical defibrillation pulse sufficient to defibrillate the heart. The defibrillation pulse is delivered in such a manner so as to avoid injuring the heart tissue immediately adjacent to the defibrillator electrode. In the preferred embodiment, the defibrillator electrode is helical; however, it is also envisioned as being a lance. Alternatively, the catheter further comprises a ground electrode, a demand pacer electrode, and a supplemental defibrillator electrode attached to the probe.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: December 19, 1995
    Assignee: British Technology Group USA Inc.
    Inventor: Leo Rubin
  • Patent number: 5374287
    Abstract: A defibrillator and demand pacer catheter is defined by a flexible, electrically nonconductive probe having an electrically conductive pathway longitudinally disposed therein. Attached to one end of the probe is a defibrillator electrode capable of anchoring the probe to the septum of a heart and of transmitting from said conductive pathway directly to the interior of the septum a portion of an electrical defibrillation pulse sufficient to defibrillate the heart. The defibrillation pulse is delivered in such a manner so as to avoid injuring the heart tissue immediately adjacent to the defibrillator electrode. In the preferred embodiment, the defibrillator electrode is helical; however, it is also envisioned as being a lance. Alternatively, the catheter further comprises a ground electrode, a demand pacer electrode, and a supplemental defibrillator electrode attached to the probe.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: December 20, 1994
    Assignee: British Technology Group USA Inc.
    Inventor: Leo Rubin
  • Patent number: 5158978
    Abstract: A method for the treatment of patients with acute cardiovascular compromise by administering a therapeutically effective amount of thyroid hormones. Methods of administration are included.
    Type: Grant
    Filed: June 18, 1991
    Date of Patent: October 27, 1992
    Assignee: British Technology Group (U.S.A.)
    Inventor: Leo Rubin