Patents by Inventor Leon Axel

Leon Axel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200225307
    Abstract: Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and reconstruction with arbitrary temporal resolution at arbitrary time points. According to such exemplary embodiment, such procedure can be performed with a combination of compressed sensing and parallel imaging to offer a significant improvement, for example in the reconstruction of highly undersampled data. It is also possible to provide an exemplary procedure for highly-accelerated dynamic magnetic resonance imaging using Golden-Angle radial sampling and multicoil compressed sensing reconstruction, called Golden-angle Radial Sparse Parallel MRI (GRASP).
    Type: Application
    Filed: March 30, 2020
    Publication date: July 16, 2020
    Inventors: Ricardo Otazo, Li Feng, Tobias Block, Hersh Chandarana, Leon Axel, Daniel K. Sodickson
  • Patent number: 10605878
    Abstract: Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and reconstruction with arbitrary temporal resolution at arbitrary time points. According to such exemplary embodiment, such procedure can be performed with a combination of compressed sensing and parallel imaging to offer a significant improvement, for example in the reconstruction of highly undersampled data. It is also possible to provide an exemplary procedure for highly-accelerated dynamic magnetic resonance imaging using Golden-Angle radial sampling and multicoil compressed sensing reconstruction, called Golden-angle Radial Sparse Parallel MRI (GRASP).
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: March 31, 2020
    Assignee: New York Univesity
    Inventors: Ricardo Otazo, Li Feng, Tobias Block, Hersh Chandarana, Leon Axel, Daniel K. Sodickson
  • Patent number: 10545208
    Abstract: An exemplary system, method and computer-accessible medium can be provided for generating an image(s) of a tissue(s) that can include, for example, receiving magnetic resonance imaging information regarding the tissue(s) based on a golden-angle radial sampling procedure, sorting and synchronizing the MRI information into at least two dimensions, and generating the image(s) of the tissue(s) based on the sorted and synchronized information. The tissue(s) include cardiac tissue and respiratory-affected tissue. The MRI information can include a motion of the cardiac tissue and a motion of the respiratory tissue.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: January 28, 2020
    Assignee: New York University
    Inventors: Leon Axel, Li Feng, Ricardo Otazo, Daniel Sodickson
  • Publication number: 20190064296
    Abstract: Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and reconstruction with arbitrary temporal resolution at arbitrary time points. According to such exemplary embodiment, such procedure can be performed with a combination of compressed sensing and parallel imaging to offer a significant improvement, for example in the reconstruction of highly undersampled data. It is also possible to provide an exemplary procedure for highly-accelerated dynamic magnetic resonance imaging using Golden-Angle radial sampling and multicoil compressed sensing reconstruction, called Golden-angle Radial Sparse Parallel MRI (GRASP).
    Type: Application
    Filed: March 19, 2018
    Publication date: February 28, 2019
    Inventors: Ricardo Otazo, Li Feng, Tobias Block, Hersh Chandarana, Leon Axel, Daniel K. Sodickson
  • Patent number: 9921285
    Abstract: Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and reconstruction with arbitrary temporal resolution at arbitrary time points. According to such exemplary embodiment, such procedure can be performed with a combination of compressed sensing and parallel imaging to offer a significant improvement, for example in the reconstruction of highly undersampled data. It is also possible to provide an exemplary procedure for highly-accelerated dynamic magnetic resonance imaging using Golden-Angle radial sampling and multicoil compressed sensing reconstruction, called Golden-angle Radial Sparse Parallel MRI (GRASP).
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: March 20, 2018
    Assignee: New York University
    Inventors: Ricardo Otazo, Li Feng, Tobias Block, Hersh Chandarana, Leon Axel, Daniel K. Sodickson
  • Publication number: 20150309135
    Abstract: An exemplary system, method and computer-accessible medium can be provided for generating an image(s) of a tissue(s) that can include, for example, receiving magnetic resonance imaging information regarding the tissue(s) based on a golden-angle radial sampling procedure, sorting and synchronizing the MRI information into at least two dimensions, and generating the image(s) of the tissue(s) based on the sorted and synchronized information. The tissue(s) include cardiac tissue and respiratory-affected tissue. The MRI information can include a motion of the cardiac tissue and a motion of the respiratory tissue.
    Type: Application
    Filed: April 27, 2015
    Publication date: October 29, 2015
    Inventors: Leon Axel, Ll Feng, Ricardo Otazo, Daniel Sodickson
  • Publication number: 20150077112
    Abstract: Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and reconstruction with arbitrary temporal resolution at arbitrary time points. According to such exemplary embodiment, such procedure can be performed with a combination of compressed sensing and parallel imaging to offer a significant improvement, for example in the reconstruction of highly undersampled data. It is also possible to provide an exemplary procedure for highly-accelerated dynamic magnetic resonance imaging using Golden-Angle radial sampling and multicoil compressed sensing reconstruction, called Golden-angle Radial Sparse Parallel MRI (GRASP).
    Type: Application
    Filed: April 19, 2013
    Publication date: March 19, 2015
    Inventors: Ricardo Otazo, Li Feng, Tobias Block, Chandarana Hersh, Leon Axel, Daniel K. Sodickson
  • Patent number: 7468644
    Abstract: A gradient coil arrangement generates magnetic field gradients across the main magnetic field of a magnetic resonance imaging system and includes a first conductive member, and a second conductive member electrically coupled to the first conductive member, wherein the second conductive member forms a segment that has an approximate shape of an arc when viewed along a direction of extension of the first conductive member.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: December 23, 2008
    Assignee: New York University
    Inventor: Leon Axel
  • Patent number: 7345480
    Abstract: A method, system, and software arrangement for automatically prescribing long-axis magnetic resonance imaging (“MRI”) slices of a target are provided. An MRI image is captured along a short-axis slice of the target. Vectorial components, including slice selection, phase-encoding, and frequency encoding vectors, are extracted from the short-axis slice. Vectorial components are established for a long-axis slice using the vectorial components of the short-axis slice, by transposing the slice-selection and frequency-encoding vectors. A plurality of long-axis slice planes are defined in a manner positioned relative to the long axis slice, rotating about a long axis in a direction of a long-axis frequency encoding vector. In one exemplary embodiment, frequency and phase shifts are established for each of the long-axis slices, for use in RF transmitting and receiving.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: March 18, 2008
    Assignee: New York University
    Inventors: Vinay Manjunath Pai, Leon Axel
  • Patent number: 7215123
    Abstract: A method and system for homogenizing a main magnetic field of a magnetic resonance imaging (“MRI”) system includes obtaining a main magnetic field distribution generated by the MRI system, obtaining at least one shim magnetic field distribution generated by at least one shim coil of the MRI system, and determining a corresponding shim current based on a relationship between the main magnetic field distribution and the at least one shim magnetic field distribution.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: May 8, 2007
    Assignee: New York University
    Inventor: Leon Axel
  • Publication number: 20070090906
    Abstract: A gradient coil arrangement generates magnetic field gradients across the main magnetic field of a magnetic resonance imaging system and includes a first conductive member, and a second conductive member electrically coupled to the first conductive member, wherein the second conductive member forms a segment that has an approximate shape of an arc when viewed along a direction of extension of the first conductive member.
    Type: Application
    Filed: November 5, 2004
    Publication date: April 26, 2007
    Inventor: Leon Axel
  • Publication number: 20070063703
    Abstract: A method, system, and software arrangement for automatically prescribing long-axis magnetic resonance imaging (“MRI”) slices of a target are provided. An MRI image is captured along a short-axis slice of the target. Vectorial components, including slice selection, phase-encoding, and frequency encoding vectors, are extracted from the short-axis slice. Vectorial components are established for a long-axis slice using the vectorial components of the short-axis slice, by transposing the slice-selection and frequency-encoding vectors. A plurality of long-axis slice planes are defined in a manner positioned relative to the long axis slice, rotating about a long axis in a direction of a long-axis frequency encoding vector. In one exemplary embodiment, frequency and phase shifts are established for each of the long-axis slices, for use in RF transmitting and receiving.
    Type: Application
    Filed: November 15, 2004
    Publication date: March 22, 2007
    Inventors: Vinay Paj, Leon Axel
  • Publication number: 20050248348
    Abstract: A method and system for homogenizing a main magnetic field of a magnetic resonance imaging (“MRI”) system includes obtaining a main magnetic field distribution generated by the MRI system, obtaining at least one shim magnetic field distribution generated by at least one shim coil of the MRI system, and determining a corresponding shim current based on a relationship between the main magnetic field distribution and the at least one shim magnetic field distribution.
    Type: Application
    Filed: May 4, 2005
    Publication date: November 10, 2005
    Inventor: Leon Axel
  • Publication number: 20040073124
    Abstract: The invention relates to methods and systems for detecting QRS complex in a ECG of a patient undergoing magnetic resonance imaging and automating data acquisition in the magnetic resonance imaging machine upon detection. The method and system operates by recording an ECG signal sample from the patient, receiving a real-time ECG signal from a patient undergoing MRI and correlating the real-time ECG signal with a previously determined QRS complex template derived from the ECG signal received from the patient before undergoing MRI.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 15, 2004
    Applicant: New York University
    Inventor: Leon Axel
  • Patent number: 5217016
    Abstract: A technique for generating "optimal" radio frequency pulses for use in creating SPAMM imaging stripes. The MR imaging operator is given an opportunity to select the desired stripe parameters for the SPAMM imaging stripe so that the resulting SPAMM imaging stripe will have the desired narrowness, sharpness, flatness and the like. These parameters are then used by an optimal pulse generating system of the invention to generate the input radio frequency pulse sequence which will produce the desired stripes. This technique allows a large family of pulse sequences with fairly similar performance to be generated by simply adjusting the relative weightings of criteria such as the narrowness, sharpness, flatness and the like for the SPAMM stripes.
    Type: Grant
    Filed: April 15, 1991
    Date of Patent: June 8, 1993
    Assignee: The trustees of the University of Pennsylvania
    Inventors: Leon Axel, Meir Shinnar
  • Patent number: 5111820
    Abstract: Spatial Modulation of Magnetization (SPAMM) with two sets of tagging planes orthogonal to the image plane is used in accordance with known techniques to image two-dimensional heart wall motion with MRI. However, such techniques are modified in accordance with the invention to permit direct assessment of three-dimensional heart wall motion from two-dimensional images using a three-dimensional SPAMM technique and a phase shift SPAMM technique. The three-dimensional SPAMM technique uses a third set of tagging planes oblique to the image plane to separate within-plane motion from through-plane motion. In accordance with the 3-dimensional SPAMM technique, the displacement of the oblique magnetization lines relative to the displacement of the spatial modulation pattern in the imaging plane during a preimaging time interval is indicative of the displacement of a body portion such as a patient's heart wall through the imaging plane during the preimaging time interval. Preferably, the oblique angle is 45.degree.
    Type: Grant
    Filed: November 2, 1990
    Date of Patent: May 12, 1992
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Leon Axel, Lawrence Dougherty
  • Patent number: 5054489
    Abstract: A novel magnetic resonance imaging technique provides direct imaging of motion by spatially modulating the degree of magnetization prior to imaging. The pre-imaging pulse sequence consists of an RF pulse to produce transverse magnetization, a magnetic field gradient pulse to "wrap" the phase along the direction of the gradient and a second RF pulse to mix the modulated transverse magnetization with the longitudinal magnetization. The resulting images show periodic stripes due to the modulation. Motion between the time of striping and image formation is directly demonstrated as a corresponding displacement of the stripes. Applications include studies of heart wall motion and distinguishing slowly moving blood from thrombus.
    Type: Grant
    Filed: October 6, 1988
    Date of Patent: October 8, 1991
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Leon Axel, Lawrence Dougherty
  • Patent number: 4618827
    Abstract: An improved method for providing a high-spatial-resolution NMR image, having resolved artifact-free NMR images of chemically-shifted nuclei, includes: forming a pair of NMR images each having imaging components of each of the chemically-shifted nuclei due to projections in one of a pair of opposite directions along a common line; mirroring the imaging components of one of the NMR images about a line orthogonal to the common line; registering and combining the mirrored image and the other image to eliminate a first one of the components and thus produce a composite image containing only the other component and a negative of the other component offset by twice the chemical shift; and forming a resolved image of the other component by processing the composite image to eliminate the offset negative image. The resolved image may then be combined with one or more of the NMR images to produce a resolved image of the first component. The method requires only 2N projections to form the two N-by-N NMR images.
    Type: Grant
    Filed: September 10, 1984
    Date of Patent: October 21, 1986
    Assignee: General Electric Company
    Inventors: Rowland W. Redington, Leon Axel