Abstract: A battery system including: a first electrical energy store being configured to provide a first electrical energy output at a first voltage and being connected to a voltage conversion unit; a second electrical energy store being configured to provide a second electrical energy output at a second voltage and being connected to an output of the battery system; and the voltage conversion unit connecting the first electrical energy store and the second electrical energy store and being configured to: perform a first voltage conversion functionality, in which the voltage conversion unit is configured to convert between the first voltage and the second voltage; and perform a second voltage conversion functionality, in which the voltage conversion unit is configured to convert between a third voltage and the first or second voltage; the first voltage conversion functionality and the second voltage conversion functionality sharing circuitry of the voltage conversion unit.

Abstract: The invention relates to a modular housing unit and modular housing system for electrical cell modules, in particular for an electric vehicle. It also relates to a method of assembling the same. The modular housing unit supports an electrical cell module in an electric vehicle. The housing unit includes a base having an upper face; a wall circumscribing the base and extending away from the upper face to define a compartment opening; and a unit compartment within the upper face and the wall. The unit compartment is accessible through the compartment opening. The housing unit receives through the compartment opening at least one electrical cell module for mounting in the unit compartment. The wall is releasably mountable in an assembled position to a corresponding wall of a second housing unit so that, in the assembled position, the base of the second housing unit forms a closure of the compartment opening.

Abstract: The present disclosure provides an AAV-ITR based gene delivery system comprising (i) an AAV-ITR vector comprising a double stranded polynucleotide encoding a gene of interest flanked by ITRs and (ii) a Rep vector comprising an mRNA encoding a Rep protein such as Rep78, wherein both vectors are encapsulated, e.g., in a liposome or LNP. Such a combination of ITR vector with the expression of Rep68/78 results in amplification of the AAV-ITR vector and enhanced episomal maintenance of the vector in the cells, which provides the base for sustained transgene expression. The liposomes containing the AAV-ITR vector and Rep vector components of the gene delivery system can be targeted to one or more surface proteins on a targeted cell or tissue. The gene of interest can be, for example, chimeric antigen receptors (CAR), or antibodies. Also provided are pharmaceutical compositions, vectors, lipid compositions, kits, and methods of treatment.

Abstract: Disclosed are lipid nanoparticle (LNP) delivery systems that specifically target T cells. The LNP delivery system comprises antibodies conjugated to the surface of the LNP, e.g., via maleimide chemistry, that target at least two T cell surface proteins, e.g., CD3 and CD28. The LNP delivery system can have a single population of LNP conjugated to either a bispecific antiCD3/antiCD28 antibody, or two monospecific antiCD3 and antiCD28 antibodies, or two populations of LNP wherein each population comprises a monospecific antibody. The payload of the LNP delivery system can be, e.g., mRNA encoding chimeric antigen receptors (CAR), a linear DNA fragment or a plasmid encoding chimeric antigen receptors (CAR) or therapeutic proteins such as antibodies, components of a gene editing systems (e.g., CRISPR-Cas), small molecules, antibody-drug conjugates (ADC), and any combination thereof, either encapsulated in the LNP or attached to its surface (e.g., conjugated).

Abstract: Features are disclosed for a dynamic security seal indicating a security of an application. A computing device can receive a request to implement a dynamic security seal for an application. The computing device can validate a relationship between an entity and the application and between an image and the application. Based on validating these relationships, the computing device can generate a dynamic security seal. When implemented, the dynamic security seal may display a plurality of faces. A face of the plurality of faces may be the image. The dynamic security seal can sequentially display the plurality of faces based on various criteria.

Abstract: A battery system having an output for supplying electrical energy to an electric drive motor of a vehicle, the battery system comprising: a first electrical energy store having a first nominal voltage and being configured to provide a first electrical energy output at a first voltage, the first electrical energy store being connected to a voltage conversion unit; a second electrical energy store having a second nominal voltage, the second nominal voltage being greater than the first nominal voltage, and being configured to provide a second electrical energy output at a second voltage, the second electrical energy store being connected to the output of the battery system; and the voltage conversion unit connecting the first electrical energy store and the second electrical energy store and being configured to convert between the first voltage and the second voltage, and the voltage conversion unit being connected to the output of the battery system such that the first electrical energy store is connected to th

Abstract: Herein is disclosed, a rechargeable flow battery, wherein the flow battery comprises: first and second electrodes, separated such that ions are allowed to flow between them, wherein a first reservoir comprising or for holding a first fluid electrolyte is fluidly connected to the first electrode, to allow circulation of the first fluid electrolyte from the first reservoir to the first electrode and from the first electrode to the first reservoir; and a first current collector comprising a layer of electrically conductive material having opposing first and second sides, wherein the first electrode is disposed on the first side of the first current collector, such that electrons can flow from the electrode to the first current collector, and a first layer of dielectric material is disposed on the second side of the first current collector.

Abstract: Features are disclosed for a dynamic security seal indicating a security of an application. A computing device can receive a request to implement a dynamic security seal for an application. The computing device can validate a relationship between an entity and the application and between an image and the application. Based on validating these relationships, the computing device can generate a dynamic security seal. When implemented, the dynamic security seal may display a plurality of faces. A face of the plurality of faces may be the image. The dynamic security seal can sequentially display the plurality of faces based on various criteria.

Abstract: A box with a lid having first and second opposed pairs of downwardly projecting legs which partially overlie the sides of the box to close the same. The length of the first pair of downwardly projecting legs is less than the length of the second pair of downwardly projecting legs. A generally horizontal ledge is formed in each side of the box with the ledges of two opposed sides of the box located at one level below the lid and those of the other opposed sides at a different level below the lid. In use, the first and second pairs of legs can either be supported on either one or the other pair of opposed ledges to vary the height of the lid above ground level. Also, the lid can be removed from the box to define a stool or support surface.

Abstract: Herein is disclosed, a rechargeable flow battery, wherein the flow battery comprises: first and second electrodes, separated such that ions are allowed to flow between them, wherein a first reservoir comprising or for holding a first fluid electrolyte is fluidly connected to the first electrode, to allow circulation of the first fluid electrolyte from the first reservoir to the first electrode and from the first electrode to the first reservoir; and a first current collector comprising a layer of electrically conductive material having opposing first and second sides, wherein the first electrode is disposed on the first side of the first current collector, such that electrons can flow from the electrode to the first current collector, and a first layer of dielectric material is disposed on the second side of the first current collector.

Abstract: A hydraulic lash adjuster (HLA) sleeve configured to be received within a lifter bore of an engine block, includes a cylindrical sleeve having an outer surface defining an outer diameter, and an inner surface defining an inner diameter. The outer diameter is sized for an interference fit with the lifter bore to prevent rotation of the HLA sleeve within the lifter bore. The inner diameter is sized to receive a lifter.

Abstract: A hydraulic lash adjuster (HLA) sleeve configured to be received within a lifter bore of an engine block, includes a cylindrical sleeve having an outer surface defining an outer diameter, and an inner surface defining an inner diameter. The outer diameter is sized for an interference fit with the lifter bore to prevent rotation of the HLA sleeve within the lifter bore. The inner diameter is sized to receive a lifter.

Abstract: A box with a lid having first and second opposed pairs of downwardly projecting legs which partially overlie the sides of the box to close the same. The length of the first pair of downwardly projecting legs is less than the length of the second pair of downwardly projecting legs. A generally horizontal ledge is formed in each side of the box with the ledges of two opposed sides of the box located at one level below the lid and those of the other opposed sides at a different level below the lid. In use, the first and second pairs of legs can either be supported on either one or the other pair of opposed ledges to vary the height of the lid above ground level. Also, the lid can be removed from the box to define a stool or support surface.

Abstract: A system for determining at least one property of a fluid and ensuring measuring surfaces of the system in contact with the fluid remain free of contaminants, includes a housing within which at least one measuring surface is located. The fluid to be measured flows through the housing and contacts the measuring surface. A signal generating device operably associated with the surface provides signals indicative of the at least one fluid property. A transducer is operably associated with the housing and causes agitation of the fluid flowing through the housing so that the measuring surface can be cleaned even during fluid measurement.

Abstract: A system for determining at least one property of a fluid and ensuring measuring surfaces of the system in contact with the fluid remain free of contaminants, includes a housing within which at least one measuring surface is located. The fluid to be measured flows through the housing and contacts the measuring surface. A signal generating device operably associated with the surface provides signals indicative of the at least one fluid property. A transducer is operably associated with the housing and causes agitation of the fluid flowing through the housing so that the measuring surface can be cleaned even during fluid measurement.

Abstract: A system and method for measuring at least one property of a fluid includes a housing for receiving the fluid, a first and second spaced electrodes positioned in the housing, and an impedance modifier positioned between the first and second electrodes that changes an electrical impedance of the fluid between the electrodes. Electronic circuitry generates different waveform voltages across the electrodes and the fluid, monitors an output thereof to thereby obtain data related to impedance of the fluid for each waveform voltage; and combines data related to the outputs to create a unique identification signature for the fluid. Once signatures for known fluids have been created, they can be compared to a generated signature of an unknown fluid to identify the unknown fluid.

Abstract: A system and method for measuring the quality of a fluid includes an optical body forming a measurement surface configured for contacting the fluid to be measured; a light source for projecting radiant energy into the optical body and toward the measurement surface at a predetermined angle; an optical sensor module arranged for detecting an image of at least reflected radiant energy from the measurement surface, the optical sensor module includes a two-dimensional array of light sensors or pixels, each pixel having a plurality of brightness levels; and a processor for setting a brightness threshold value, comparing the threshold value to the brightness level of each pixel, and counting the number of pixels above and/or below the brightness threshold value.

Abstract: A system and method for measuring the quality of a fluid includes an optical body forming a measurement surface configured for contacting the fluid to be measured; a light source for projecting radiant energy into the optical body and toward the measurement surface at a predetermined angle; an optical sensor module arranged for detecting an image of at least reflected radiant energy from the measurement surface, the optical sensor module includes a two-dimensional array of light sensors or pixels, each pixel having a plurality of brightness levels; and a processor for setting a brightness threshold value, comparing the threshold value to the brightness level of each pixel, and counting the number of pixels above and/or below the brightness threshold value.

Abstract: A hands-free carrier for supporting a plurality of handled shopping bags. The carrier includes a U-shaped carrier body having a base and a pair of opposed legs joined thereto. Each of the legs terminates in a free end. Formed on each of the free ends is a hook. Each hook curves in a direction toward the base of the carrier body. The carrier body is adapted to be supported by a user with the base passing over the forearm of the user, and the hooks disposed substantially below the forearm. Each of the hooks may be inserted through the handle of a loaded shopping bag, thus allowing the user to carry the shopping bags while retaining free use of the hand.