Abstract: During catheter-based angiography, the bone and soft tissues degrade visualization of the vasculature, which is of primary interest in such medical imaging procedures. The present disclosure includes systems and methods utilizing a trained neural network to remove the bone and soft tissue densities from post-contrast images, revealing isolated vascular densities, without the need for a standard pre-injection digital mask and in the setting of patient motion. The final angiographic images may be created in real-time. Systems and methods for the training and optimization of the disclosed neural network are also described.

Abstract: An online system allows content items to be targeted based on interests associated with users. When the online system receives a request to specify targeting criteria associated with a content item, the online system provides an interface to specify targeting criteria. As the online system receives input specifying an interest for inclusion in targeting criteria, the online system retrieves stored interests associated with online system users. Each interest stored by the online system is associated with a type. For example, a type associated with a stored interest indicates whether the interest is from a set of user-generated keywords, from a set of semantic topics mapped from the keywords, or from a set of manually curated broad categories. To avoid confusion from overlap in the types of interests, the online system applies rules to stored interests matching at least a portion of the input to select a set of interests.