Patents by Inventor Leon Eckhardt

Leon Eckhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID SEQUENCING USING AFFINITY REAGENTS
    Publication number: 20240117425
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Application
    Filed: September 7, 2023
    Publication date: April 11, 2024
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang
  • Nucleic acid sequencing using affinity reagents
    Patent number: 11788138
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: October 17, 2023
    Assignees: MGI Tech Co., Ltd., BGI Shenzhen
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang
  • MASSIVELY PARALLEL SEQUENCING USING UNLABELED NUCLEOTIDES
    Publication number: 20220162693
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Application
    Filed: November 11, 2019
    Publication date: May 26, 2022
    Inventors: Snezana Drmanac, Handong Li, Matthew J. Callow, Leon Eckhardt, Scott Gablenz, Radoje Drmanac, Ping Zhou
  • NUCLEIC ACID SEQUENCING USING AFFINITY REAGENTS
    Publication number: 20210254150
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Application
    Filed: October 29, 2020
    Publication date: August 19, 2021
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang
  • Nucleic acid sequencing using affinity reagents
    Patent number: 10851410
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: December 1, 2020
    Assignees: MGI Tech Co., Ltd., BGI Shenzhen
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang
  • STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES
    Publication number: 20180223358
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Application
    Filed: January 4, 2018
    Publication date: August 9, 2018
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang, Quan Ding