Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.

Abstract: A wind powered turbine has a conduit. A middle conduit portion is located between inlet and outlet conduit portions, having a main inlet and outlet of the conduit, respectively. A rotor having a shaft with blades extending therefrom is located in the middle conduit portion. The blades are located completely within the middle conduit portion. Preferably, a splitter is located in the inlet conduit portion to provide upper and lower sub-tunnels that both feed into the middle conduit portion. Upper and lower interior walls of the middle conduit portion have substantially circular plane shapes that are substantially centered at the rotational axis of the shaft. Upper and lower clearance gaps are located between the blades and the upper and lower interior walls, respectively. The main outlet is preferably higher than the main inlet. Preferably, a generator is located on each side of the conduit and rotatably coupled to the shaft.

Abstract: A wind powered turbine has a conduit. A middle conduit portion is located between inlet and outlet conduit portions, having a main inlet and outlet of the conduit, respectively. A rotor having a shaft with blades extending therefrom is located in the middle conduit portion. The blades are located completely within the middle conduit portion. Preferably, a splitter is located in the inlet conduit portion to provide upper and lower sub-tunnels that both feed into the middle conduit portion. Upper and lower interior walls of the middle conduit portion have substantially circular plane shapes that are substantially centered at the rotational axis of the shaft. Upper and lower clearance gaps are located between the blades and the upper and lower interior walls, respectively. The main outlet is preferably higher than the main inlet. Preferably, a generator is located on each side of the conduit and rotatably coupled to the shaft.

Abstract: An improved downcomer for vapor liquid contact towers. The downcomer is formed between generally semi-conical walls and the wall of the tower. The downcomer outlet is formed by the lower edge of the generally semi-conical walls and the wall of the tower with the lower edge of the generally semi-conical walls being closer to the wall of the tower at the center of the downcomer outlet than at the opposing end portions of the downcomer outlet so that more liquid flows through the opposing end portions of the downcomer outlet than through the center of the downcomer outlet thereby providing a substantially uniform flow of liquid across the tray adjacent the downcomer.

Abstract: A method of and apparatus for deentrainment and mass transfer in a chemical process tower. The apparatus comprises a structured packing layer assembled with a second type of packing layer disposed adjacent the underside of a process tower tray. The dual layer assembly reduces liquid entrainment in ascending vapor flow and provides an additional region for mass transfer.