Patents by Inventor Leon Fernando Garcia-Martinez

Leon Fernando Garcia-Martinez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manipulation of Cytokine Levels Using CD83 Gene Products
    Publication number: 20110144309
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Application
    Filed: November 8, 2010
    Publication date: June 16, 2011
    Applicant: Celltech R&D, Inc.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Modulating immune responses
    Patent number: 7872103
    Abstract: The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: January 18, 2011
    Assignee: Celltech R & D, Limited
    Inventors: Leon Fernando Garcia-Martinez, Yuching Chen, Dawn Andrews
  • Manipulation of cytokine levels using CD83 gene products
    Patent number: 7850968
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: December 14, 2010
    Assignee: Celltech R&D Limited
    Inventors: Fred Ramsdell, Sean C Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Modulating Immune Responses
    Publication number: 20100249380
    Abstract: The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
    Type: Application
    Filed: February 3, 2010
    Publication date: September 30, 2010
    Applicant: CELLTECH R&D LIMITED
    Inventors: LEON FERNANDO GARCIA-MARTINEZ, YUCHING CHEN, DAWN ANDREWS
  • Antibodies to CD83
    Patent number: 7700740
    Abstract: The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: April 20, 2010
    Inventors: Leon Fernando Garcia-Martinez, Yuching Chen, Dawn Andrews
  • Manipulation of Cytokine Levels Using CD83 Gene Products
    Publication number: 20100081797
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 1, 2010
    Applicant: CELLTECH R&D, INC.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Manipulation of cytokine levels using CD83 gene products
    Patent number: 7618629
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: November 17, 2009
    Assignee: Celltech R&D, Inc.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Modulating immune responses
    Publication number: 20080299122
    Abstract: The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
    Type: Application
    Filed: May 23, 2007
    Publication date: December 4, 2008
    Applicant: UCB SA
    Inventors: Leon Fernando Garcia-Martinez, Yuching Chen, Dawn Andrews
  • Modulating immune responses
    Publication number: 20040185040
    Abstract: The invention provides methods for modulating the immune system using anti-CD83 antibodies that can influence CD83 function.
    Type: Application
    Filed: November 21, 2003
    Publication date: September 23, 2004
    Applicant: Celltech R & D Limited
    Inventors: Leon Fernando Garcia-Martinez, Yuching Chen, Dawn Andrews