Abstract: Embodiments of the present invention include a control and analysis system, a signal generation and detection apparatus, or reader for capturing, processing and analyzing images of samples having resonance light scattering (RLS) particle labels. An analyzer/reader includes an illumination system having a unique shutter/aperture assembly for delivering precise patterns of light to a sample, a computer controlled X-Y stage, and a detection system comprising a CCD camera to allow separation and analysis of detected light that contains information from gold and/or silver RLS labels. Alternative embodiments include linear scanning apparatus and simplified apparatus for low density samples.

Abstract: The present invention is directed to deconvolution and normalization of assay data. The present invention includes a control and analysis system, used in conjunction with a signal generation and detection apparatus, for capturing, processing and analyzing images of samples having resonance light scattering (RLS) particle labels. The control and analysis system processes instructions and algorithms for performing multiplexed assays of two or more colors, for example, to allow separation and analysis of detected light that contains information from two or more different types or sizes of RLS particles. The multiplexing analysis software is preferably incorporated within the system of the present invention, and the multiplexing analysis is preferably performed in real-time during a scanning or assay procedure. The invention provides for a computer readable medium containing instructions for carrying out the same.

Abstract: The present invention is directed to deconvolution and normalization of assay data. The present invention includes a control and analysis system, used in conjunction with a signal generation and detection apparatus, for capturing, processing and analyzing images of samples having resonance light scattering (RLS) particle labels. The control and analysis system processes instructions and algorithms for performing multiplexed assays of two or more colors, for example, to allow separation and analysis of detected light that contains information from two or more different types or sizes of RLS particles. The multiplexing analysis software is preferably incorporated within the system of the present invention, and the multiplexing analysis is preferably performed in real-time during a scanning or assay procedure. The invention provides for a computer readable medium containing instructions for carrying out the same.

Abstract: Embodiments of the present invention include a control and analysis system, a signal generation and detection apparatus, or reader for capturing, processing and analyzing images of samples having resonance light scattering (RLS) particle labels. An analyzer/reader includes an illumination system having a unique shutter/aperture assembly for delivering precise patterns of light to a sample, a computer controlled X-Y stage, and a detection system comprising a CCD camera to allow separation and analysis of detected light that contains information from gold and/or silver RLS labels. Alternative embodiments include linear scanning apparatus and simplified apparatus for low density samples.

Abstract: An internal conduit vehicle comprises two coaxially aligned dual-vector wheels mounted to each end of a chassis. The wheels include multiple, elongated rollers each positioned at an angle around a hub assembly. Two motors mounted to opposite ends of the chassis are rotationally coupled to a hub assembly. A motor control system mounted to the chassis drives the motors so that the wheels counter-rotate with equal, but opposite torque, thereby driving the vehicle axially through a conduit.

Abstract: A child's safety guard for baluster-type banisters designed to prevent any portion of a child's body from falling through or being jammed between adjacent balusters and railings, without degrading the aesthetic appearance of the banisters. The guard comprises a set of thin, substantially stiff panels of sheet material having a parallelogram configuration capable of being adjustably overlapped along adjacent edges to cover substantially the entire space facing the landing between the railings. The panels are secured in their overlapped position by a lacing threaded through a series of drilled openings along the top and bottom edges of the panels and around the balusters. The panels are preferably fabricated of a clear, plastic material, but can be made in any desired color.

Abstract: An underwater acoustic communication system provides an operator with adjable frequency diversity so that data rates may be tailored to specific multipath environments. Transmitted messages are sent with precursor transmission/reception synchronization data and transmission parameter data so that the receiving communication end will recognize when message data starts, tone length as-well-as the frequency diversity of the transmitted message. Timing is extracted from the data to compensate for Doppler shift.