Patents by Inventor Leon Johannes De Windt

Leon Johannes De Windt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • microRNAS FOR THE TREATMENT OF HEART DISEASES
    Publication number: 20180214475
    Abstract: The invention relates to the field of molecular biology and medicine, more specifically the invention is directed towards the treatment, delay and amelioration of heart diseases. More in particular, microRNAs are provided that induce cardiac regeneration by inducing cell cycle proliferation of cardiomyocytes, thereby treating or ameliorating heart diseases associated with a loss of cardiomyocytes or cardiomyocyte function. Such diseases include myocardial infarction, cardiomyopathy of ischemic or non-ischemic origin, myocarditis and heart failure. More in particular, the invention relates to a composition comprising a microRNA selected from the group consisting of microRNA 106b, microRNA 93 or microRNA 25 and the complements thereof, for use in the treatment, prevention, delay or amelioration of a heart disease.
    Type: Application
    Filed: August 18, 2016
    Publication date: August 2, 2018
    Inventors: Leon Johannes De Windt, Ellen Dirkx, Mauro Giacca
  • Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
    Patent number: 9611480
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: April 4, 2017
    Assignees: Universiteit Maastricht, Academisch Ziekenhuis Maastricht
    Inventors: Leon Johannes De Windt, Hamid El Azzouzi
  • MEANS AND METHODS FOR COUNTERACTING, DELAYING AND/OR PREVENTING ADVERSE ENERGY METABOLISM SWITCHES IN HEART DISEASE
    Publication number: 20140357699
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Application
    Filed: July 16, 2014
    Publication date: December 4, 2014
    Inventors: Leon Johannes De Windt, Hamid El Azzouzi
  • Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
    Patent number: 8815822
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: August 26, 2014
    Assignees: Universiteit Maastricht, Academisch Ziekenhuis Maastricht
    Inventors: Leon Johannes De Windt, Hamid El Azzouzi
  • Means and methods for counteracting, delaying and/or preventing heart disease
    Patent number: 8383603
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: February 26, 2013
    Assignees: Universiteit Maastricht, Academisch Ziekehuis Maastricht
    Inventors: Leon Johannes De Windt, Paula Alexandra Da Costa Martins
  • Cardiac hypertrophy
    Patent number: 8367342
    Abstract: The invention provides means and methods for at least in part inducing, counteracting, preventing and/or investigating cardiac hypertrophy.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: February 5, 2013
    Assignee: Lead Pharma Drug Development IP B.V.
    Inventors: Paula Alexandra Da Costa Martins, Leon Johannes De Windt
  • MEANS AND METHODS FOR COUNTERACTING, DELAYING AND/OR PREVENTING ADVERSE ENERGY METABOLISM SWITCHES IN HEART DISEASE
    Publication number: 20120141442
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Application
    Filed: August 6, 2009
    Publication date: June 7, 2012
    Applicants: Academisch Ziekenhuis Maastricht, Universiteit Maastricht
    Inventors: Leon Johannes De Windt, Hamid El Azzouzi
  • MEANS AND METHODS FOR COUNTERACTING, DELAYING AND/OR PREVENTING HEART DISEASE
    Publication number: 20110110902
    Abstract: The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides alternative methods for counteracting, diminishing, treating, delaying and/or preventing heart disease.
    Type: Application
    Filed: June 16, 2009
    Publication date: May 12, 2011
    Applicant: BioMedbooster B.V.
    Inventors: Leon Johannes De Windt, Paula Alexandra Da Costa Martins
  • Cardiac Hypertrophy
    Publication number: 20100055732
    Abstract: The invention provides means and methods for at least in part inducing, counteracting, preventing and/or investigating cardiac hypertrophy.
    Type: Application
    Filed: December 19, 2007
    Publication date: March 4, 2010
    Applicant: Lead Pharma Drug Development IP B.V.
    Inventors: Paula Alexandra Da Costa Martins, Leon Johannes De Windt