Abstract: A wearable light therapy device for administering light into the eyes of a wearer, and a method of managing circadian rhythm disorders, including sleep onset insomnia and early morning awakening insomnia, jet-lag and shift work fatigue, the light therapy device comprising a pair of side supporting arms with a bridging component therebetween, wherein each supporting arm comprises a free end and a hinged end, the free end being for mounting upon a respective ear of a wearer, and the hinged end being pivotally attached to one end of the bridging component; and characterised in that the bridging component comprises a raised nose portion configured between lower opposed lateral portions, each lateral portion having at least one light aperture for directing light from at least one light source into the eyes of a wearer, the nose portion being mountable upon the nose of a wearer during use such that the lateral portions are generally below the eyes of the wearer.

Abstract: A novel apparatus and method is described for sleep monitoring and control by providing tactile stimulation to a user as the user attempts to fall asleep which can be employed for intensive sleep retraining for the treatment of insomnia. A motion response to the tactile stimulation from the user is sensed indicating the user is still awake. The tactile stimulation is periodically repeated and the motion response is evaluated until sleep onset is determined. Following a relatively short set time asleep (e.g. approximately 3 minutes) the user is awakened and the process is reinitiated within a half hour. The technique can be implemented in a small device configuration comparable to a large ring which can be held to a single finger of the user by a band. The single finger both receives the tactile stimulation and provides a motion response and can provide feedback directly to the user.

Abstract: A novel apparatus and method is described for sleep monitoring and control by providing tactile stimulation to a user as the user attempts to fall asleep which can be employed for intensive sleep retraining for the treatment of insomnia. A motion response to the tactile stimulation from the user is sensed indicating the user is still awake. The tactile stimulation is periodically repeated and the motion response is evaluated until sleep onset is determined. Following a relatively short set time asleep (e.g. approximately 3 minutes) the user is awakened and the process is reinitiated within a half hour. The technique can be implemented in a small device configuration comparable to a large ring which can be held to a single finger of the user by a band. The single finger both receives the tactile stimulation and provides a motion response and can provide feedback directly to the user.

Abstract: An apparatus for administering light to effect re-timing of the human body clock is disclosed. In one form, the apparatus includes two pairs of light emitting diodes having an emission wavelength in the range 450 nm to 530 nm and a frame adapted to be worn on the face of a wearer. The frame is arranged to support the two pairs of light emitting diodes so that one pair of the light emitting diodes is supported adjacent a surface of each eye of the wearer. The light emitting diodes of each pair project a light output that illuminates a different area of the retina of a respective eye and are spaced apart so as to provide a viewing zone therebetween.

Abstract: A method of treating androgen-related disorders in an animal which comprises administering to the animal dihydrotestosterone level decreasing amounts of a compound of formula (I): ##STR1## wherein R is H or F; R.sup.1 is selected from the group consisting of --H; straight or branched chain lower alkyl; hydroxyl; --OCOR.sup.3 ; and O--(C.sub.1 -C.sub.6 alkyl); wherein R.sup.3 is --H, C.sub.1 -C.sub.10 straight or branched chain alkyl group, phenyl, phenyl alkylene having straight or branched chain C.sub.1 -C.sub.6 alkylene, C.sub.5 -C.sub.10 cycloalkyl or C.sub.6 -C.sub.10 cycloalkyl alkylene; R.sup.2 is H.sub.2, methylene, ethylidene, .alpha.-CH.sub.3 (H), .beta.-CH.sub.3 (H), .alpha.-(OH)(H) or the acetonide derived from the 16.alpha.,17.alpha.-dihydroxy derivative, and n is 1 or 2.