Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

Abstract: A chain driven diffuser for use in a sugar extraction process, the diffuser including a diffuser floor, a plurality of chain ladder assemblies being displaceable relative to the diffuser floor, with each chain Id-der assembly comprising two opposing chains being driven by drive sprockets characterized in that at least some of the drive sprockets of the diffuser are driven independently from some of the other drive sprockets of the diffusor.

Abstract: A rotary distribution apparatus includes a stationary, cylindrical inner core (27), and a rotatable, cylindrical outer shell (25) disposed about the inner core with the inner core (27) and the outer shell defining a plurality of annular fluid distribution chambers therebetween. The apparatus furthermore includes a rotatable indexing disc (23) having a plurality of flow passages provided therethrough, connection ports of which are in flow communication with ports in the outer shell (25), and a stationary indexing disc (22) having a plurality of flow passages provided therethrough, connection ports of which are in flow communication with suitable process vessels. The rotary distribution apparatus includes a driving arrangement that comprises a stationary shaft (28) to which the stationary core (27) is secured and a rotatable sleeve (24) rotatable about the stationary shaft (28), the rotatable sleeve (24) driving the rotatable outer shell (25) and the rotatable indexing disc (23).

Abstract: A chain driven diffuser for use in a sugar extraction process, the diffuser including a diffuser floor, a plurality of chain ladder assemblies being displaceable relative to the diffuser floor, with each chain Id-der assembly comprising two opposing chains being driven by drive sprockets characterized in that at least some of the drive sprockets of the diffuser are driven independently from some of the other drive sprockets of the diffusor.

Abstract: A rotary distribution apparatus includes a stationary, cylindrical inner core (27), and a rotatable, cylindrical outer shell (25) disposed about the inner core with the inner core (27) and the outer shell defining a plurality of annular fluid distribution chambers therebetween. The apparatus furthermore includes a rotatable indexing disc (23) having a plurality of flow passages provided therethrough, connection ports of which are in flow communication with ports in the outer shell (25), and a stationary indexing disc (22) having a plurality of flow passages provided therethrough, connection ports of which are in flow communication with suitable process vessels. The rotary distribution apparatus includes a driving arrangement that comprises a stationary shaft (28) to which the stationary core (27) is secured and a rotatable sleeve (24) rotatable about the stationary shaft (28), the rotatable sleeve (24) driving the rotatable outer shell (25) and the rotatable indexing disc (23).

Abstract: A hydro electric generating device that is mobile. The hydro electric generating device may include a water tank with a turbine generator suspended within it. Water may be pumped from the bottom of the water tank and to the top of the water tank. The rotating water supply may be directed onto rotor blades of the turbine generator and thereby generate electricity.

Abstract: A Snap N Place sign system and method for supporting a sign message includes a sign substrate associated with a number of rubber nipple fasteners and a lens. The sign message and the lens further include mounting holes placed at their corners for securely holding the sign message in association with the sign substrate and lens. The rubber nipple fastener can be pulled through the mounting holes in the lens utilizing a relatively low insertion force. The rubber nipple fasteners can be driven axially into the mounting holes in the lens with a flexible tab engaging the lens and flexing as they move through the hole in the lens. The rubber nipple fastener can be specifically designed such that the force required to install or push the rubber nipple fastener through the mounting hole is relatively low thereby facilitating ergonomic considerations. The Snap N Place sign system is capable of holding signs of a variety of thicknesses and sizes.

Abstract: An indexing arrangement (10) includes a rotor (12) ; a stator (14) spaced from the rotor; a rotary seal (16) located between the rotor and the stator, with the seal being rotatable with the rotor; means for urging the rotary seal into sealing contact with the stator; ports (20, 24, 22) in the rotor, in the stator and in the rotary seal; and connecting means (26) for connecting respective ports (20) in the rotor with respective ports in the rotary seal; so that in use fluid can flow through the ports in the rotor, into the ports in the rotary seal via the connecting means, and out through the ports (24) in the stator.

Abstract: This invention relates to a continuous vacuum pan (also sometimes referred to as an evaporative crystallizer) for use in the sugar processing industry, and to a heat exchanger used inside the continuous vacuum pan. The invention also relaters to the heat exchanger as used in other applications in the sugar processing industry. The heat exchanger includes a massecuite flow path for conveying massecuite therethrough, and a heat transfer medium flow path for receiving a heat transfer medium to enable heat transfer to the massecuite flow path. The heat exchanger is characterized therein that a periphery thereof is surrounded by an insulated zone in order to prevent heat transfer from the heat transfer medium flow path to the environment.

Abstract: A method, apparatus, and system are disclosed. The apparatus includes a shaft operable to be held by an entity and a housing extending from one end of the shaft and operable to allow multiple deterrents to be emitted there from. The housing includes a rotation member coupled to a rim portion of the housing and operable to rotate along a track portion within the rim portion. The apparatus further includes a transparent material coupled to the rotation member and operable to allow a deterrent to travel there through. The housing includes a light source coupled to the transparent material and operable to emit a light. Further, the apparatus includes a swivel meshed between the shaft and the housing and operable to allow the housing oscillate in an angular direction. Each deterrent is operable to obscure an image of the entity captured by filming equipment.

Abstract: This invention relates to a continuous vacuum pan (also sometimes referred to as an evaporative crystallizer) for use in the sugar processing industry, and to a heat exchanger used inside the continuous vacuum pan. The invention also relaters to the heat exchanger as used in other applications in the sugar processing industry. The heat exchanger includes a massecuite flow path for conveying massecuite therethrough, and a heat transfer medium flow path for receiving a heat transfer medium to enable heat transfer to the massecuite flow path. The heat exchanger is characterized therein that a periphery thereof is surrounded by an insulated zone in order to prevent heat transfer from the heat transfer medium flow path to the environment.

Abstract: An herbicidal composition containing (a) florasulam and (b) at least one preemergent annual grass herbicide selected from the group consisting of dithiopyr and pendimethalin provides synergistic control of selected weeds in turf.

Abstract: A Snap N Place sign system and method for supporting a sign message includes a sign substrate associated with a number of rubber nipple fasteners and a lens. The sign message and the lens further include mounting holes placed at their corners for securely holding the sign message in association with the sign substrate and lens. The rubber nipple fastener can be pulled through the mounting holes in the lens utilizing a relatively low insertion force. The rubber nipple fasteners can be driven axially into the mounting holes in the lens with a flexible tab engaging the lens and flexing as they move through the hole in the lens. The rubber nipple fastener can be specifically designed such that the force required to install or push the rubber nipple fastener through the mounting hole is relatively low thereby facilitating ergonomic considerations. The Snap N Place sign system is capable of holding signs of a variety of thicknesses and sizes.

Abstract: An indexing arrangement (10) includes a rotor (12); a stator (14) spaced from the rotor; a rotary seal (16) located between the rotor and the stator, with the seal being rotatable with the rotor; means for urging the rotary seal into sealing contact with the stator; ports (20, 24, 22) in the rotor, in the stator and in the rotary seal; and connecting means (26) for connecting respective ports (20) in the rotor with respective ports in the rotary seal; so that in use fluid can flow through the ports in the rotor, into the ports in the rotary seal via the connecting means, and out through the ports (24) in the stator.

Abstract: A method, apparatus, and system are disclosed. The apparatus includes a shaft operable to be held by an entity and a housing extending from one end of the shaft and operable to allow multiple deterrents to be emitted there from. The housing includes a rotation member coupled to a rim portion of the housing and operable to rotate along a track portion within the rim portion. The apparatus further includes a transparent material coupled to the rotation member and operable to allow a deterrent to travel there through. The housing includes a light source coupled to the transparent material and operable to emit a light. Further, the apparatus includes a swivel meshed between the shaft and the housing and operable to allow the housing oscillate in an angular direction. Each deterrent is operable to obscure an image of the entity captured by filming equipment.

Abstract: The present invention provides enhanced security to internal components in a main access compartment of a fuel dispenser. Both a primary lock on a main panel, that secures the main access compartment, and a hidden second lock, hidden inside a lower compartment of the fuel dispenser, must be bypassed to gain access to the internal components, thus providing enhanced security. The lower compartment is also protected by a lock, which must be bypassed in order to gain access to the hidden second lock in an attempt to bypass the hidden second lock. This locking arrangement provides greater security than prior art methods since three locks, including a hidden lock, must be bypassed to breach security and gain access to the internal components in the main access compartment of the fuel dispenser.

Abstract: A rotary distribution apparatus includes a fixed inner distribution member (12) with inner conduit zone; a rotatable distribution member (16) rotatable about the fixed inner distribution member; a plurality of fluid distribution chambers (18) located between the fixed inner distribution member and the rotatable outer distribution member; each fluid distribution chamber having a fixed port (20) in the fixed inner distribution member to which a fixed supply or return conduit for a fluid can in use be connected and at least one distribution port (22) in the rotatable outer distribution member; at least one indexing arrangement (24) including a rotatable indexing member (26) and a fixed indexing member (28); a plurality of passageways (30, 32, 38, 40) extending through each of the rotatable and fixed indexing members (26, 28), the plurality of passageways each having indexing ports (30.2, 32.2, 38.2, 40.2) and connection ports (30.1, 32.1, 38.1, 40.

Abstract: Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A rotary distribution apparatus includes a fixed inner distribution member (12) with inner conduit zone; a rotatable distribution member (16) rotatable about the fixed inner distribution member; a plurality of fluid distribution chambers (18) located between the fixed inner distribution member and the rotatable outer distribution member; each fluid distribution chamber having a fixed port (20) in the fixed inner distribution member to which a fixed supply or return conduit for a fluid can in use be connected and at least one distribution port (22) in the rotatable outer distribution member; at least one indexing arrangement (24) including a rotatable indexing member (26) and a fixed indexing member (28); a plurality of passageways (30, 32, 38, 40) extending through each of the rotatable and fixed indexing members (26, 28), the plurality of passageways each having indexing ports (30.2, 32.2, 38.2, 40.2) and connection ports (30.1, 32.1, 38.1, 40.