Patents by Inventor Leon T. Van Den Broeke

Leon T. Van Den Broeke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic peptides and methods of use for treating and preventing cancer
    Patent number: 9206245
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: December 8, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jay A. Berzofsky, Leon T. van den Broeke, Crystal L. Mackall, Lee J. Helman
  • IMMUNOGENIC PEPTIDES AND METHODS OF USE FOR TREATING AND PREVENTING CANCER
    Publication number: 20140141004
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Application
    Filed: December 20, 2013
    Publication date: May 22, 2014
    Applicant: The U.S.A as represented by the Secretary, Department of Health and Human Services
    Inventors: Jay A. Berzofsky, Leon T. van den Broeke, Crystal L. Mackall, Lee J. Helman
  • Immunogenic peptides and methods of use for treating and preventing cancer
    Patent number: 8614304
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: December 24, 2013
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Serives
    Inventors: Jay A. Berzofsky, Leon T. Van den Broeke, Crystal Mackall, Lee J. Helman
  • IMMUNOGENIC PEPTIDES AND METHODS OF USE FOR TREATING AND PREVENTING CANCER
    Publication number: 20110081352
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Application
    Filed: December 13, 2010
    Publication date: April 7, 2011
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health & Human Service
    Inventors: Jay A. Berzofsky, Leon T. Van den Broeke, Crystal Mackall, Lee J. Helman
  • Immunogenic peptides and methods of use for treating and preventing cancer
    Patent number: 7867977
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Grant
    Filed: October 24, 2006
    Date of Patent: January 11, 2011
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jay A. Berzofsky, Leon T. Van Den Broeke, Crystal MacKall, Lee J. Helman
  • IMMUNOGENIC PEPTIDES AND METHODS OF USE FOR TREATING AND PREVENTING CANCER
    Publication number: 20090117116
    Abstract: Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
    Type: Application
    Filed: October 24, 2006
    Publication date: May 7, 2009
    Applicant: Government of the United States of America, Represented by the Secretary of Health and Human..
    Inventors: Jay A. Berzofsky, Leon T. Van Den Broeke, Crystal MacKall, Lee J. Helman
  • Cosmetic and dermatological sunscreen compositions containing thiols and/or thiol derivates
    Patent number: 5728373
    Abstract: Cosmetic and dermatological light protection formulations, characterized by an active content of thiols and/or thiol derivatives.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: March 17, 1998
    Assignees: Beiersdorf AG, Rijksuniversiteit Leiden
    Inventors: Dirk Alert, Heinrich Gers-Barlag, Leon T. Van Den Broeke, Gerard M. J. Beijersbergen van Henegouwen