Patents by Inventor Leonard A. Mermel

Leonard A. Mermel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230414806
    Abstract: Systems and methods for cleaning and disinfecting contaminated tube lumens are described herein. One system includes an ultraviolet light source and a sterile fluid reservoir fluidly coupled to a liquid light guide. The system is configured to allow simultaneous access and propagation of ultraviolet light and fluid in a tube having a lumen to be cleaned and disinfected. The light guide can be moved inside the tube and simultaneously emit ultraviolet light through its walls and at its distal end into the interior of the contaminated tube. A flush of sterile fluid from an open end of the liquid light guide removes debris and micro-organism detached from the inner surface during light exposure. The sterile fluid can be a high refractive index ionic solution promoting light propagation.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 28, 2023
    Inventors: Leonard A. Mermel, Jimmy Bak
  • Patent number: 11723997
    Abstract: Systems and methods for cleaning and disinfecting contaminated tube lumens are described herein. One system includes an ultraviolet light source and a sterile fluid reservoir fluidly coupled to a liquid light guide. The system is configured to allow simultaneous access and propagation of ultraviolet light and fluid in a tube having a lumen to be cleaned and disinfected. The light guide can be moved inside the tube and simultaneously emit ultraviolet light through its walls and at its distal end into the interior of the contaminated tube. A flush of sterile fluid from an open end of the liquid light guide removes debris and micro-organism detached from the inner surface during light exposure. The sterile fluid can be a high refractive index ionic solution promoting light propagation.
    Type: Grant
    Filed: January 13, 2022
    Date of Patent: August 15, 2023
    Assignee: Bak & Mermel LLC
    Inventors: Leonard A. Mermel, Jimmy Bak
  • Publication number: 20220175990
    Abstract: Systems and methods for cleaning and disinfecting contaminated tube lumens are described herein. One system includes an ultraviolet light source and a sterile fluid reservoir fluidly coupled to a liquid light guide. The system is configured to allow simultaneous access and propagation of ultraviolet light and fluid in a tube having a lumen to be cleaned and disinfected. The light guide can be moved inside the tube and simultaneously emit ultraviolet light through its walls and at its distal end into the interior of the contaminated tube. A flush of sterile fluid from an open end of the liquid light guide removes debris and micro-organism detached from the inner surface during light exposure. The sterile fluid can be a high refractive index ionic solution promoting light propagation.
    Type: Application
    Filed: January 13, 2022
    Publication date: June 9, 2022
    Inventors: Leonard A. Mermel, Jimmy Bak
  • Patent number: 11246953
    Abstract: Systems and methods for cleaning and disinfecting contaminated tube lumens are described herein. One system includes an ultraviolet light source and a sterile fluid reservoir fluidly coupled to a liquid light guide. The system is configured to allow simultaneous access and propagation of ultraviolet light and fluid in a tube having a lumen to be cleaned and disinfected. The light guide can be moved inside the tube and simultaneously emit ultraviolet light through its walls and at its distal end into the interior of the contaminated tube. A flush of sterile fluid from an open end of the liquid light guide removes debris and micro-organism detached from the inner surface during light exposure. The sterile fluid can be a high refractive index ionic solution promoting light propagation.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: February 15, 2022
    Assignee: Bak & Mermel LLC
    Inventors: Leonard A. Mermel, Jimmy Bak
  • Publication number: 20210244840
    Abstract: Systems and methods for cleaning and disinfecting contaminated tube lumens are described herein. One system includes an ultraviolet light source and a sterile fluid reservoir fluidly coupled to a liquid light guide. The system is configured to allow simultaneous access and propagation of ultraviolet light and fluid in a tube having a lumen to be cleaned and disinfected. The light guide can be moved inside the tube and simultaneously emit ultraviolet light through its walls and at its distal end into the interior of the contaminated tube. A flush of sterile fluid from an open end of the liquid light guide removes debris and micro-organism detached from the inner surface during light exposure. The sterile fluid can be a high refractive index ionic solution promoting light propagation.
    Type: Application
    Filed: July 25, 2019
    Publication date: August 12, 2021
    Inventors: Leonard A. Mermel, Jimmy Bak
  • Patent number: 9234248
    Abstract: This invention comprises a multiplex-capable oligonucleotide which is capable of hybridizing to at least one of the C. difficile tcdB, tcdC, or cdtB genes, wherein, wherein said primer consists of a sequence selected from the group consisting of SEQ ID NOS: 1 through 9, or a sequence that exhibits no more than one substitution of a base to a sequence selected from the group consisting of SEQ ID NOS: 1 through 9 and method for polymerase chain reaction (PCR) determining of the presence of a toxigenic strain of C. difficile in a biological sample utilizing said probes.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: January 12, 2016
    Assignee: Brown University
    Inventors: Aartik Sarma, Anubhav Tripathi, Leonard Mermel, Aleksey Novikov, Leah Seward, Jennifer Fieber
  • Publication number: 20120252029
    Abstract: This invention comprises a multiplex-capable oligonucleotide which is capable of hybridizing to at least one of the C. difficile tcdB, tcdC, or cdtB genes, wherein, wherein said primer consists of a sequence selected from the group consisting of SEQ ID NOS: 1 through 9, or a sequence that exhibits no more than one substitution of a base to a sequence selected from the group consisting of SEQ ID NOS: 1 through 9 and method for polymerase chain reaction (PCR) determining of the presence of a toxigenic strain of C. difficile in a biological sample utilizing said probes.
    Type: Application
    Filed: July 15, 2010
    Publication date: October 4, 2012
    Applicant: Brown University
    Inventors: Aartik Sarma, Anubhav Tripathi, Leonard Mermel, Aleksey Novikov, Leah Seward, Jennifer Fieber