Patents by Inventor Leonard B. Crast, Jr.

Leonard B. Crast, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pradimicin derivatives
    Patent number: 5227370
    Abstract: The present invention provides pradimicin analogs which exhibit improved water solubility relative to parent compounds. These novel agents are useful in treatment of fungal infections.
    Type: Grant
    Filed: December 3, 1991
    Date of Patent: July 13, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Hajime Kamachi, Seiji Iimura, Satsuki Okuyama, Shimpei Aburaki, Takayuki Naito, Yasutsugu Ueda, Leonard B. Crast, Jr., Amarendra B. Mikkilineni
  • 3-propenyl cephalosporin solvates
    Patent number: 4694079
    Abstract: 7-[(D)-2-Amino-2-(4-hydroxyphenyl)acetamido]-3-[(Z)-1-propenyl]ceph-3-em-4- carboxylic acid in the form of its crystalline dimethylformamide solvate (1/1.5) has been provided.
    Type: Grant
    Filed: July 29, 1985
    Date of Patent: September 15, 1987
    Assignee: Bristol-Myers Company
    Inventor: Leonard B. Crast, Jr.
  • Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids
    Patent number: 4125716
    Abstract: Compounds of the formula ##STR1## in which R.sup.1 is hydrogen or hydroxy are potent antibacterial agents.
    Type: Grant
    Filed: December 16, 1977
    Date of Patent: November 14, 1978
    Assignee: Bristol-Myers Company
    Inventors: Leonard B. Crast, Jr., Robert G. Graham