Abstract: The invention provides antiangiogenic compositions and methods of use. The general methods deliver an antiangiogen to a patient determined to be in need thereof, comprising the steps of: (a) administering to the patient a predetermined amount of an antiangiogenic, optionally substituted DIM; and (b) detecting in the patient a resultant antiangiogenic response.

Abstract: The invention provides immune response activating compositions and methods of use. The general methods deliver an immune response activator to a patient determined to be in need thereof, comprising the steps of: (a) administering to the patient a predetermined amount of an immune response activating, optionally substituted DIM; and (b) detecting in the patient a resultant immune response activation, such as an increase in T-cell proliferation, NO production, cytokine production, cytokine receptor expression, or cytokine signaling.

Abstract: The invention provides antiandrogenic compositions and methods of use. The general methods deliver an antiandrogen to a host determined to be in need thereof by contacting the host with an effective amount of an antiandrogenic, optionally substituted 3,3?-diindolylmethane (DIM); and detecting a resultant antiandrogenic response in the host. The method may further comprise, prior to the contacting step, determining that the host is in need of the antiandrogen.