Patents by Inventor Leonard Bloom

Leonard Bloom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for composite cell-based implants
    Publication number: 20040117033
    Abstract: This invention is a method for the implantation of a combination of cells or cell-microcarrier aggregates wherein one component comprises a solid implantable construct and a second component comprises an injectable formulation. For example, in one embodiment, the solid implant may be first implanted to fill the majority of the cavity receiving the implant, and then cells or cell-microcarrier aggregates in an injectable format, with or without the addition of gelling materials to promote rapid gelling in situ, may be injected into spaces surrounding the solid implant in order to secure the solid implant in the site and/or to promote rapid adherence and/or integration of the solid implant to surrounding tissues. Also contemplated in this embodiment is that the cellular composition of the injectable component may differ from that of the solid component.
    Type: Application
    Filed: December 9, 2003
    Publication date: June 17, 2004
    Inventors: Carmelita G. Frondoza, David S. Hungerford, Alan H. Shikani, Abraham J. Domb, David J. Fink, Leonard Bloom
  • Method for composite cell-based implants
    Patent number: 6662805
    Abstract: This invention is a method for the implantation of a combination of cells or cell-microcarrier aggregates wherein one component comprises a solid implantable construct and a second component comprises an injectable formulation. For example, in one embodiment, the solid implant may be first implanted to fill the majority of the cavity receiving the implant, and then cells or cell-microcarrier aggregates in an injectable format, with or without the addition of gelling materials to promote rapid gelling in situ, may be injected into spaces surrounding the solid implant in order to secure the solid implant in the site and/or to promote rapid adherence and/or integration of the solid implant to surrounding tissues. Also contemplated in this embodiment is that the cellular composition of the injectable component may differ from that of the solid component.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: December 16, 2003
    Assignees: The Johns Hopkins University, Chondros, Inc.
    Inventors: Carmelita G. Frondoza, David S. Hungerford, Alan H. Shikani, Abraham J. Domb, David J. Fink, Leonard Bloom
  • Method for composite cell-based implants
    Publication number: 20010051834
    Abstract: This invention is a method for the implantation of a combination of cells or cell-microcarrier aggregates wherein one component comprises a solid implantable construct and a second component comprises an injectable formulation. For example, in one embodiment, the solid implant may be first implanted to fill the majority of the cavity receiving the implant, and then cells or cell-microcarrier aggregates in an injectable format, with or without the addition of gelling materials to promote rapid gelling in situ, may be injected into spaces surrounding the solid implant in order to secure the solid implant in the site and/or to promote rapid adherence and/or integration of the solid implant to surrounding tissues. Also contemplated in this embodiment is that the cellular composition of the injectable component may differ from that of the solid component.
    Type: Application
    Filed: August 6, 2001
    Publication date: December 13, 2001
    Applicant: Chondros, Inc.
    Inventors: Carmelita G. Frondoza, David S. Hungerford, Alan H. Shikani, Abraham J. Domb, David J. Fink, Leonard Bloom