Patents by Inventor Leonard C. Harrison

Leonard C. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pancreatic islet cell growth factors
    Patent number: 6967100
    Abstract: The present invention relates generally to growth factors and more particularly to growth factors which are capable of stimulating or otherwise facilitating formation of insulin-secreting cells. The identification of these growth factors permits the development of protocols to culture cells in vitro for transplantation into mammalian and in particular human subjects with insulin-dependent type 1 diabetes or related conditions. It is further contemplated that the endogenous expression of growth factors required for the development of insulin-producing cells may be manipulated in vivo, by the appropriate administration of agents including genetic agents capable of regulating the expression of growth factors in pancreatic duct epithelial cells. The growth factors ray also be administered to subjects with type 1 diabetes to stimulate the proliferation and differentiation of pancreatic cells into insulin-secreting cells.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: November 22, 2005
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Leonard C. Harrison, Fang-Xu Jiang, Edouard Guy Stanley, Leonel Jorge Gonez
  • Pancreatic islet cell growth factors
    Publication number: 20020072115
    Abstract: The present invention relates generally to growth factors and more particularly to growth factors which are capable of stimulating or otherwise facilitating formation of insulin-secreting cells. The identification of these growth factors permits the development of protocols to culture cells in vitro for transplantation into mammalian and in particular human subjects with insulin-dependent type 1 diabetes or related conditions. It is further contemplated that the endogenous expression of growth factors required for the development of insulin-producing cells may be manipulated in vivo, by the appropriate administration of agents including genetic agents capable of regulating the expression of growth factors in pancreatic duct epithelial cells. The growth factors ray also be administered to subjects with type 1 diabetes to stimulate the proliferation and differentiation of pancreatic cells into insulin-secreting cells.
    Type: Application
    Filed: February 16, 2001
    Publication date: June 13, 2002
    Applicant: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
    Inventors: Leonard C. Harrison, Fang-Xu Jiang, Edouard Guy Stanley, Leonel Jorge Gonez