Patents by Inventor Leonard C. Waite

Leonard C. Waite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20130029901
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: July 30, 2012
    Publication date: January 31, 2013
    Inventors: William M. PIERCE, JR., K. Grant TAYLOR, Leonard C. WAITE, Kevyn MERTEN
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20120083440
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: October 5, 2011
    Publication date: April 5, 2012
    Inventors: William M. Pierce, JR., K. Grant Taylor, Leonard C. Waite, Kevyn Merten
  • Methods and compounds for the targeted delivery of agents to bone for interaction therewith
    Patent number: 8071575
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: December 6, 2011
    Assignee: University of Louisville Research Foundation
    Inventors: William M. Pierce, Jr., K. Grant Taylor, Leonard C. Waite
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20090118164
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: February 22, 2008
    Publication date: May 7, 2009
    Inventors: William M. Pierce, JR., K. Grant Taylor, Leonard C. Waite
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20080221070
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion. The Bone Active Portion is derived from an estrogenic agent. Compounds can also include a Blocking Group (RP) that reduces or eliminates the estrogenic activity of the Bone Active Portion.
    Type: Application
    Filed: March 6, 2008
    Publication date: September 11, 2008
    Inventors: William M. Pierce, K. Grant Taylor, Leonard C. Waite
  • Bone targeting compounds for delivering agents to bone for interaction therewith
    Patent number: 7399789
    Abstract: The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the bone for interaction therewith.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: July 15, 2008
    Assignee: University of Louisville Research Foundation
    Inventors: William M. Pierce, Leonard C. Waite, K. Grant Taylor
  • Bone targeting compounds for delivering agents to the bone for interaction therewith
    Patent number: 7196220
    Abstract: The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the bone for interaction therewith.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: March 27, 2007
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: William M. Pierce, Jr., Leonard C. Waite, K. Grant Taylor
  • Bone targeted inhibitors of carbonic anhydrase
    Patent number: 5641762
    Abstract: The present invention relates to novel compounds useful for the treatment and prophylaxis of degenerative bone disorders and to the preparation thereof. These compounds are particularly characterized by two active moieties, the first of which possesses "bone-seeking" affinity and the second which is an inhibition of the enzyme carbonic anhydrase and/or an inhibitor of bone resorption. The novel compounds of this invention can be administered as pharmaceutically acceptable compositions and in convenient dosage unit form in a method for the treatment and prophylaxis of degenerative bone disorders.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: June 24, 1997
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William M. Pierce, Jr., Leonard C. Waite