Patents by Inventor Leonard F. Pease

Leonard F. Pease has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230310662
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.
    Type: Application
    Filed: May 24, 2023
    Publication date: October 5, 2023
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Patent number: 11684681
    Abstract: Disclosed are methods of detecting eosinophil degranulation in the respiratory tract of subjects. Also, disclosed are methods of producing medical images of the respiratory tract of subjects. The method can include administering radiolabeled heparin to the respiratory tract of subjects, wherein the radiolabeled heparin binds to one or more eosinophil granule protein in the mucosal tissue of the respiratory tract.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: June 27, 2023
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Publication number: 20220054662
    Abstract: Also disclosed are methods
    Type: Application
    Filed: July 19, 2021
    Publication date: February 24, 2022
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Patent number: 11065351
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: July 20, 2021
    Assignee: University of Utah Research Foundation
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Publication number: 20200306798
    Abstract: Mesofluidic separator assemblies are provided that can include at least a pair of supports configured to extend within a pressure differential axis, and at least one level of a plurality of members extending between the pair of supports. Separator assemblies are also provided that can include at least individual members of the plurality defining a plurality of levels extending from a first level configured to have initial contact with the fluid to be separated and a last level configured to have final contact with the fluid to be separated. Assemblies are also provided that can include each member in a set of members being aligned along one axis that is neither parallel nor normal to the pressure differential axis. Assemblies are provided that can include a conduit configured to facilitate the flow of fluid along a pressure differential axis with the conduit defining at least one cross sectional area that is open. Methods for size separating particles within a fluid are provided.
    Type: Application
    Filed: April 25, 2019
    Publication date: October 1, 2020
    Applicant: Battelle Memorial Institute
    Inventors: Leonard F. Pease, Xiao-Ying Yu, Timothy G. Veldman, Matthew S. Fountain, Michael J. Minette, Carolyn A. Burns, Nathan R. Phillips, Jason E. Serkowski
  • Publication number: 20200016282
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.
    Type: Application
    Filed: July 3, 2019
    Publication date: January 16, 2020
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Patent number: 10376602
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagitis or other organs in a subject.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: August 13, 2019
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Publication number: 20180036440
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagitis or other organs in a subject.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 8, 2018
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Patent number: 9789212
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: October 17, 2017
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Publication number: 20150132221
    Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 14, 2015
    Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
  • Publication number: 20150132227
    Abstract: Disclosed are compositions and methods for related to echogenic contrast agents. Also disclosed are methods and compositions for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for producing a medical image of a tissue. Also disclosed are methods of monitoring the progression of eosinophilic esophagitis in a subject before, during, and after treatment.
    Type: Application
    Filed: April 18, 2013
    Publication date: May 14, 2015
    Inventors: Leonard F. Pease, Hedieh Saffari, Kathryn Peterson, Kristin Leiferman, Anne Kennedy, Russell Morris Condie, Gerald Gleich
  • Publication number: 20150057517
    Abstract: Disclosed are devices, compositions, and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 26, 2015
    Inventors: Leonard F. Pease, Kathryn Peterson, Hedieh Saffari, Joseph R. Heath, Gerald Gleich, Kristin Leiferman
  • Publication number: 20120132891
    Abstract: Precision quantum dot clusters and methods for producing and tuning quantum dot clusters are described herein. Also described herein are materials and devices, including photovoltaic devices, that may include one or more quantum dot clusters.
    Type: Application
    Filed: July 14, 2011
    Publication date: May 31, 2012
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Leonard F. Pease, III, Jeeseong C. Hwang
  • Patent number: 7588657
    Abstract: In accordance with the invention, substrate-supported linear arrays are formed by the steps of adhering a thin layer of polymer between a pair of substrates and separating the substrates perpendicular to the layer. The polymer layer separates to form substrate-supported polymer gratings on both substrates, each grating having a period proportional to the thickness of the layer. The process has been used to make gratings with periods in the sub-micron range or larger over areas covering square centimeters.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: September 15, 2009
    Assignee: Princeton University
    Inventors: William B Russel, Stephen Y Chou, Leonard F Pease, III, Parikshit A Deshpande
  • Publication number: 20080125771
    Abstract: Methods and apparatuses for contouring, shaping and/or directionally shrinking tissue by selective application of energy are disclosed herein. One embodiment of a method of contouring tissue includes determining a contraction direction along which the tissue is to be preferentially contracted and applying energy to a plurality of discrete elongated exposed regions of tissue spaced apart from each other among non-exposed regions of tissue. At least one of the exposed regions can be oriented such that a longitudinal dimension of the exposed regions is generally transverse to the contraction direction.
    Type: Application
    Filed: November 27, 2007
    Publication date: May 29, 2008
    Inventors: Michael Lau, Leonard F. Pease