Patents by Inventor Leonard F. Pease
Leonard F. Pease has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240360005Abstract: Systems for separating components of a mixture are provided which can include: a conduit system having at least one linear section including a length of opposing sidewalls defining a volume configured to receive a flow of mixed materials entering along a proximate end of the length and exiting along a distal end of the length; and a tortured path defining at least one series of members extending in line across the volume from one sidewall of the volume and inwardly toward the distal end defining an angle other than normal from the one sidewall. Methods for separating components of a mixture are provided which can include providing a mixture of components into the tortured path to separate larger components from smaller components of the mixture and concentrate the larger components toward an opposing sidewall of the conduit.Type: ApplicationFiled: April 29, 2024Publication date: October 31, 2024Applicant: Battelle Memorial InstituteInventors: Leonard F. Pease, Michael J. Minette, Carolyn A. Burns, Jason E. Serkowski, Nathan R. Phillips
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Publication number: 20240359367Abstract: Material separator assemblies are provided which can include: a conduit system configured to be arranged in relation to body forces; the system can include at least one linear section, which can include a length of opposing sidewalls defining a volume configured to receive a flow of mixed materials entering along a proximate end of the length, proceeding along the length, and exiting along a distal end of the length; and an exposed body force slide surface extending in the direction of the flow of materials along the linear section. Methods for separating components of a mixture can include providing a mixture of components to a conduit having an exposed body force slide surface within a linear section of the conduit.Type: ApplicationFiled: April 29, 2024Publication date: October 31, 2024Applicant: Battelle Memorial InstituteInventors: Leonard F. Pease, Michael J. Minette, Carolyn A. Burns, Raymond S. Addleman, Jason E. Serkowski
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Publication number: 20240359118Abstract: Systems and methods for separating components of a mixture are provided. The systems can include at least one section that defines a tortured path configured to provide some components in one direction along the section and other components in another direction along the section. Methods can provide for the separation of bubbles within a liquid matrix, liquid separation, liquid/solid separation, and/or solids separation.Type: ApplicationFiled: July 8, 2024Publication date: October 31, 2024Applicant: Battelle Memorial InstituteInventors: Leonard F. Pease, Xiao-Ying Yu, Timothy G. Veldman, Matthew S. Fountain, Michael J. Minette, Carolyn A. Burns, Nathan R. Phillips, Jason E. Serkowski, Judith A. Bamberger, Raymond S. Addleman
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Publication number: 20230310662Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.Type: ApplicationFiled: May 24, 2023Publication date: October 5, 2023Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Patent number: 11684681Abstract: Disclosed are methods of detecting eosinophil degranulation in the respiratory tract of subjects. Also, disclosed are methods of producing medical images of the respiratory tract of subjects. The method can include administering radiolabeled heparin to the respiratory tract of subjects, wherein the radiolabeled heparin binds to one or more eosinophil granule protein in the mucosal tissue of the respiratory tract.Type: GrantFiled: July 19, 2021Date of Patent: June 27, 2023Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Publication number: 20220054662Abstract: Also disclosed are methodsType: ApplicationFiled: July 19, 2021Publication date: February 24, 2022Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Patent number: 11065351Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.Type: GrantFiled: July 3, 2019Date of Patent: July 20, 2021Assignee: University of Utah Research FoundationInventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Publication number: 20200306798Abstract: Mesofluidic separator assemblies are provided that can include at least a pair of supports configured to extend within a pressure differential axis, and at least one level of a plurality of members extending between the pair of supports. Separator assemblies are also provided that can include at least individual members of the plurality defining a plurality of levels extending from a first level configured to have initial contact with the fluid to be separated and a last level configured to have final contact with the fluid to be separated. Assemblies are also provided that can include each member in a set of members being aligned along one axis that is neither parallel nor normal to the pressure differential axis. Assemblies are provided that can include a conduit configured to facilitate the flow of fluid along a pressure differential axis with the conduit defining at least one cross sectional area that is open. Methods for size separating particles within a fluid are provided.Type: ApplicationFiled: April 25, 2019Publication date: October 1, 2020Applicant: Battelle Memorial InstituteInventors: Leonard F. Pease, Xiao-Ying Yu, Timothy G. Veldman, Matthew S. Fountain, Michael J. Minette, Carolyn A. Burns, Nathan R. Phillips, Jason E. Serkowski
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Publication number: 20200016282Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagus or other organs in a subject.Type: ApplicationFiled: July 3, 2019Publication date: January 16, 2020Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Patent number: 10376602Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagitis or other organs in a subject.Type: GrantFiled: September 29, 2017Date of Patent: August 13, 2019Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Publication number: 20180036440Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. In another aspect, disclosed is a method of diagnosing eosinophilic esophagitis or eosinophilic diseases in a subject, comprising detecting an eosinophil granule protein in the mucosal tissue of the esophagitis or other organs in a subject.Type: ApplicationFiled: September 29, 2017Publication date: February 8, 2018Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Patent number: 9789212Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.Type: GrantFiled: May 17, 2013Date of Patent: October 17, 2017Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Publication number: 20150132227Abstract: Disclosed are compositions and methods for related to echogenic contrast agents. Also disclosed are methods and compositions for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for producing a medical image of a tissue. Also disclosed are methods of monitoring the progression of eosinophilic esophagitis in a subject before, during, and after treatment.Type: ApplicationFiled: April 18, 2013Publication date: May 14, 2015Inventors: Leonard F. Pease, Hedieh Saffari, Kathryn Peterson, Kristin Leiferman, Anne Kennedy, Russell Morris Condie, Gerald Gleich
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Publication number: 20150132221Abstract: Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.Type: ApplicationFiled: May 17, 2013Publication date: May 14, 2015Inventors: Leonard F. Pease, Hedieh Saffari, Gerald J. Gleich, Kristin M. Leiferman, Kathryn A. Peterson, Russell Morris Condie
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Publication number: 20150057517Abstract: Disclosed are devices, compositions, and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment.Type: ApplicationFiled: March 27, 2013Publication date: February 26, 2015Inventors: Leonard F. Pease, Kathryn Peterson, Hedieh Saffari, Joseph R. Heath, Gerald Gleich, Kristin Leiferman
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Publication number: 20120132891Abstract: Precision quantum dot clusters and methods for producing and tuning quantum dot clusters are described herein. Also described herein are materials and devices, including photovoltaic devices, that may include one or more quantum dot clusters.Type: ApplicationFiled: July 14, 2011Publication date: May 31, 2012Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Leonard F. Pease, III, Jeeseong C. Hwang
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Patent number: 7588657Abstract: In accordance with the invention, substrate-supported linear arrays are formed by the steps of adhering a thin layer of polymer between a pair of substrates and separating the substrates perpendicular to the layer. The polymer layer separates to form substrate-supported polymer gratings on both substrates, each grating having a period proportional to the thickness of the layer. The process has been used to make gratings with periods in the sub-micron range or larger over areas covering square centimeters.Type: GrantFiled: September 29, 2004Date of Patent: September 15, 2009Assignee: Princeton UniversityInventors: William B Russel, Stephen Y Chou, Leonard F Pease, III, Parikshit A Deshpande
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Publication number: 20080125771Abstract: Methods and apparatuses for contouring, shaping and/or directionally shrinking tissue by selective application of energy are disclosed herein. One embodiment of a method of contouring tissue includes determining a contraction direction along which the tissue is to be preferentially contracted and applying energy to a plurality of discrete elongated exposed regions of tissue spaced apart from each other among non-exposed regions of tissue. At least one of the exposed regions can be oriented such that a longitudinal dimension of the exposed regions is generally transverse to the contraction direction.Type: ApplicationFiled: November 27, 2007Publication date: May 29, 2008Inventors: Michael Lau, Leonard F. Pease