Patents by Inventor Leonard Gomella

Leonard Gomella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detecting micrometastasis of prostate cancer
    Patent number: 5939258
    Abstract: A method of diagnosing prostate micrometastasis is provided by the present invention whereby nucleic acids from a tissue sample from a patient are isolated, nucleic acids from the tissue sample specific for prostate cancer are amplified, or a signal generated by hybridization of a probe specific to a prostate cancer specific nucleic acid is amplified; and detection of amplified nucleic acids is indicative of micrometastasis of prostate cancer.
    Type: Grant
    Filed: December 12, 1996
    Date of Patent: August 17, 1999
    Assignee: Thomas Jefferson University
    Inventors: Carlo Croce, Leonard Gomella, S. Grant Mulholland, Jose G. Moreno, Rainer Fischer
  • Methods of detecting micrometastasis of prostate cancer
    Patent number: 5688649
    Abstract: A method of diagnosing prostate metastasis is provided by the present invention whereby RNA from a patient's blood is isolated and amplified using a pair of primers which are complementary to regions of the prostate specific antigen gene. The presence or absence of amplified RNA is detected and the presence of amplified RNA is indicative micrometastasis of prostate cancer.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: November 18, 1997
    Assignee: Thomas Jefferson University
    Inventors: Carlo Croce, Leonard Gomella, S. Grant Mulholland, Jose G. Moreno, Rainer Fischer
  • Nucleic acid primers for detecting micrometastasis of prostate cancer
    Patent number: 5674682
    Abstract: Oligonucleotides for and a method of diagnosing prostate micrometastasis are provided by the present invention whereby nucleic acids from a tissue sample from a patient are isolated, nucleic acids from the tissue sample specific for prostate cancer are amplified, or a signal generated by hybridization of a probe specific to a prostate cancer specific nucleic acid is amplified; and detection of amplified nucleic acids is indicative of micrometastasis of prostate cancer.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: October 7, 1997
    Assignee: Thomas Jefferson University
    Inventors: Carlo Croce, Leonard Gomella, S. Grant Mulholland, Jose G. Moreno, Rainer Fischer
  • Methods of detecting micrometastasis of prostate cancer
    Patent number: 5506106
    Abstract: A method of diagnosing prostate metastasis is provided by the present invention whereby RNA from a patient's blood is isolated and amplified using a pair of primers which are complementary to regions of the prostate specific antigen gene. The presence or absence of amplified RNA is detected and the presence of amplified RNA is indicative micrometastasis of prostate cancer.
    Type: Grant
    Filed: August 23, 1994
    Date of Patent: April 9, 1996
    Assignee: Thomas Jefferson University
    Inventors: Carlo Croce, Leonard Gomella, S. Grant Mulholland, Jose G. Moreno, Rainer Fischer