Patents by Inventor Leonard L. Kaplan

Leonard L. Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200101028
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: April 8, 2019
    Publication date: April 2, 2020
    Applicant: Phio Pharmaceuticals Corp.
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Patent number: 10300027
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: May 28, 2019
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Publication number: 20150057362
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: November 4, 2014
    Publication date: February 26, 2015
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Publication number: 20110268761
    Abstract: The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
    Type: Application
    Filed: February 25, 2011
    Publication date: November 3, 2011
    Inventors: William R. Levis, Leonard L. Kaplan, John G. Callahan
  • Publication number: 20040092592
    Abstract: Linking Magnesium ions to Nitric Oxide precursor L-Arginine, chemically 2-amino-5-guanidino valeric acid, with a platelet aggregation inhibitor compound such as, but not limited to acetylsalicylic acid or clopidogrel bisulfate, unexpectedly results in a pharmaceutically stabilized compositions with extended shelf life to be taken orally to provide gradual release vasodilatory and anti-platelet aggregation pharmacological activity with reduced potential for producing gastrointestinal lesions. L-Arginine releases ADNO (Arginine derived Nitric Oxide) in the coronary artery epithelium as EDRF (endothelium dependent relaxing factor) to dilate the arteries to promote blood flow to the myocardium, and the platelet aggregation inhibitor such acetylsalicylic acid or clopidogrel and others of this class of drugs inhibits or antagonizes the aggregation adhesion of platelets in the blood stream.
    Type: Application
    Filed: November 8, 2002
    Publication date: May 13, 2004
    Inventor: Leonard L. Kaplan
  • Patent number: 6455586
    Abstract: Topical drug compositions, containing contact sensitizing agents as the active components of the subject patent compositions, can provide a pharmacological action that induces a delayed hypersensitization reaction resulting in stimulation of cell mediated immunity when applied to the skin. The preferred composition contains, but is not limited to, Diphenylcyclpropenone as a preferred embodiment of the class of contact sensitizing drugs applied to the skin in an optimally prepared pharmaceutical formulation with controlled absorption properties to reach the peripheral circulation resulting in increases in CD4+ helper T cells of benefit to immunocompromised patients.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: September 24, 2002
    Inventors: Leonard L. Kaplan, William R. Levis
  • Publication number: 20020128326
    Abstract: Topical drug compositions, containing contact sensitizing agents as the active components of the subject patent compositions, can provide a pharmacological action that induces a delayed hypersensitization reaction resulting in stimulation of cell mediated immunity when applied to the skin. The preferred composition contains, but is not limited to, Diphenylcyclpropenone as a preferred embodiment of the class of contact sensitizing drugs applied to the skin in an optimally prepared pharmaceutical formulation with controlled absorption properties to reach the peripheral circulation resulting in increases in CD4+ helper T cells of benefit to immunocompromised patients.
    Type: Application
    Filed: December 13, 1999
    Publication date: September 12, 2002
    Inventors: LEONARD L. KAPLAN, WILLIAM R. LEVIS
  • Patent number: 4383986
    Abstract: An antipruritic, astringent and anti-inflammatory composition is provided. The composition is useful in the treatment of hemorrhoid symptoms.
    Type: Grant
    Filed: August 17, 1981
    Date of Patent: May 17, 1983
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Darius D. Dubash, Leonard L. Kaplan, George A. Ziets
  • Patent number: 4155868
    Abstract: A completely water soluble effervescent denture cleanser tablet containing both an enzyme and one or more active oxygen compounds. The enzyme in said tablet is resistant to premature inactivation by the oxidizing agents in the tablet during storage and in use and therefore has the added enzymatic cleansing power not possessed by conventional tablets containing only the active oxygen compounds. A method for preparing enzyme-containing denture cleanser tablets in which the activity of the enzyme is usefully retained is also described.
    Type: Grant
    Filed: March 2, 1977
    Date of Patent: May 22, 1979
    Assignee: Johnson & Johnson
    Inventors: Leonard L. Kaplan, Norman A. Levin