Patents by Inventor Leonard Larry Winneroski, Jr.

Leonard Larry Winneroski, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (Trifluoromethyl)pyrimidine-2-amine compounds
    Patent number: 11773067
    Abstract: The present invention provides a compound of Formula I: wherein R1 is hydrogen or methyl; and R2 is: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, diabetic peripheral neuropathic pain, and osteoarthritis pain.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: October 3, 2023
    Assignee: Eli Lilly and Company
    Inventors: Daryl Lynn Smith, Leonard Larry Winneroski, Jr.
  • (TRIFLUOROMETHYL)PYRIMIDINE-2-AMINE COMPOUNDS
    Publication number: 20220372003
    Abstract: The present invention provides a compound of Formula I: wherein R1 is hydrogen or methyl; and R2 is: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, diabetic peripheral neuropathic pain, and osteoarthritis pain.
    Type: Application
    Filed: July 25, 2022
    Publication date: November 24, 2022
    Inventors: Daryl Lynn Smith, Leonard Larry Winneroski, JR.
  • (trifluoromethyl)pyrimidine-2-amine compounds
    Patent number: 11414389
    Abstract: The present invention provides a compound of Formula I: wherein R1 is hydrogen or methyl; and R2 is: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, diabetic peripheral neuropathic pain, and osteoarthritis pain.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: August 16, 2022
    Assignee: Eli Lilly and Company
    Inventors: Daryl Lynn Smith, Leonard Larry Winneroski, Jr.
  • (TRIFLUOROMETHYL)PYRIMIDINE-2-AMINE COMPOUNDS
    Publication number: 20210347738
    Abstract: The present invention provides a compound of Formula I: wherein R1 is hydrogen or methyl; and R2 is: or a pharmaceutically acceptable salt thereof, useful for treating pain, including chronic pain, chronic lower back pain, diabetic peripheral neuropathic pain, and osteoarthritis pain.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 11, 2021
    Inventors: Daryl Lynn Smith, Leonard Larry Winneroski, JR.
  • 6-fluoro-2-methylbenzo[d]thiazol-5-yl compounds
    Patent number: 10836773
    Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: November 17, 2020
    Assignee: Eli Lilly and Company
    Inventors: Nicolas Jacques Francois Dreyfus, Jose Eduardo Lopez, Leonard Larry Winneroski, Jr., Eric Michael Woerly
  • 6-Fluoro-2-Methylbenzo[d]thiazol-5-yl Compounds
    Publication number: 20200354370
    Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 12, 2020
    Inventors: Nicolas Jacques Francois Dreyfus, Jose Eduardo Lopez, Leonard Larry Winneroski, JR., Eric Michael Woerly
  • 6-fluoro 2-methylbenzo[d]thiazol-5-yl compounds
    Patent number: 10752632
    Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: August 25, 2020
    Assignee: Eli Lilly and Company
    Inventors: Nicolas Jacques Francois Dreyfus, Jose Eduardo Lopez, Leonard Larry Winneroski, Jr., Eric Michael Woerly
  • 6-Fluoro-2-Methylbenzo[d]thiazol-5-yl Compounds
    Publication number: 20200095254
    Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 26, 2020
    Inventors: Nicolas Jacques Francois Dreyfus, Jose Eduardo Lopez, Leonard Larry Winneroski, JR., Eric Michael Woerly
  • Selective BACE1 inhibitors
    Patent number: 9522923
    Abstract: The present invention provides a compound of Formula II: or a pharmaceutically acceptable salt thereof, that are inhibitors of BACE.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: December 20, 2016
    Assignee: Eli Lilly and Company
    Inventors: Simon James Richards, Erik James Hembre, Jose Eduardo Lopez, Leonard Larry Winneroski, Jr., Timothy Andrew Woods, Jennifer Anne McMahon
  • SELECTIVE BACE1 INHIBITORS
    Publication number: 20160244465
    Abstract: The present invention provides a compound of Formula II: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 25, 2016
    Inventors: Simon James Richards, Erik James Hembre, Jose Eduardo Lopez, Leonard Larry Winneroski, Jr., Timothy Andrew Woods, Jennifer Anne McMahon
  • BACE inhibitors
    Patent number: 9169271
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: October 27, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Erik James Hembre, Dustin James Mergott, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • BACE INHIBITORS
    Publication number: 20150210716
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 2, 2015
    Publication date: July 30, 2015
    Inventors: Steven James GREEN, Erik James HEMBRE, Dustin James MERGOTT, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20150157641
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 11, 2015
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • BACE inhibitors
    Patent number: 9029367
    Abstract: The present invention provides a compound of Formula III: Formula III wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof, which is useful for treating Alzheimer's disease.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: May 12, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Erik James Hembre, Dustin James Mergott, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8987254
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: March 24, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Dustin James Mergott, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • BACE INHIBITORS
    Publication number: 20140371212
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 11, 2014
    Publication date: December 18, 2014
    Inventors: Steven James GREEN, Erik James HEMBRE, Dustin James MERGOTT, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140350245
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 7, 2014
    Publication date: November 27, 2014
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8889856
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: November 18, 2014
    Assignee: Eli Lilly and Company
    Inventors: James Peter Beck, Steven James Green, Jose Eduardo Lopez, Brian Michael Mathes, Dustin James Mergott, Warren Jaye Porter, Zoran Rankovic, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8841293
    Abstract: The present invention provides a compound of Formula I: Formula I wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: September 23, 2014
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Dustin James Mergott, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140275044
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 18, 2014
    Applicant: Eli Lilly and Company
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.